Inheritance. Flashcards

1
Q

How does DNA control cell functions?

A

DNA controls cell function by controlling the production of proteins (including enzymes, membrane carriers, and neurotransmitter receptors).

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2
Q

What does the sequence of bases in a gene determine?

A

A sequence of bases in a gene determines the sequence of amino acids used to make a specific protein.

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3
Q

What do different shapes of amino acids give?

A

Different shapes of amino acids give different shapes to protein molecules e.g. hemoglobin, amylase, and lipase.

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4
Q

Why are many genes in a particular cell not expressed?

A

Most body cells in an organism contain the same genes, but many genes in a particular cell are not expressed because the cell only makes the specific proteins it needs e.g. genes for making heart muscle are also in the brain but are not switched on.

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5
Q

Describe the six steps of protein synthesis.

A
  • The gene coding for the protein remains in the nucleus.
  • Messenger RNA (mRNA) is a copy of a gene.
  • The mRNA molecules are made in the nucleus and move to the cytoplasm.
  • The mRNA passes through ribosomes.
  • The ribosome assembles amino acids into protein molecules.
  • The specific sequence of amino acids is determined by the sequence of bases in the mRNA.
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6
Q

What is a haploid nucleus?

A

A haploid nucleus is a nucleus containing a single set of chromosomes e.g. in gametes i.e. a sperm and an egg.

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7
Q

What is a diploid nucleus?

A

A diploid nucleus is a nucleus containing two sets of chromosomes e.g. in body cells. In a diploid cell, there is a pair of each type of chromosome.

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8
Q

In a human diploid cell, how many pairs are there?

A

In a human diploid cell, there are 23 pairs.

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9
Q

What is mitosis?

A

Mitosis is nuclear division giving rise to genetically identical cells.

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10
Q

What happens during cell division?

A

When cells divide, the old cell divides into two new daughter cells. The nucleus divides first then the cytoplasm.

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11
Q

What is the role of meiosis?

A
  • Meiosis results in genetic variation.
  • Meiosis is involved in the production of gametes for sexual production.
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12
Q

What are the four roles of mitosis?

A
  • Growth all over animals and in plants in the cambium and in meristems at root and stem tips.
  • Repair of damaged tissues e.g. wounds.
  • Replacmenr of worn out cells e.g. red blood cells.
  • Asexual reproduction: in plants, fungi and bacteria by binary fission.
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13
Q

What happens during mitosis?

A

The two daughter cells separate so that each new cell gets a copy of each chromosome and maintains the chromosome number.

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14
Q

What are stem cells?

A

Stem cells are unspecialized cells that divide by mitosis to produce daughter cells that can become specialized for specific functions e.g. muscle cells, skin cells, etc.

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15
Q

Where do adults have stem cells and what are they for?

A

Adults have stem cells in bone marrow to produce red blood cells and phagocytes, and under the outer layer of skin to produce new skin cells.

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16
Q

What happens as an embryo in regards to stem cells?

A

As the embryo develops, the cells begin to take on different roles. Once a cell has differentiated it cannot change its role.

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17
Q

What do medical researches hope to use stem cells for?

A

Medical researchers are hoping to use stem cells to cure diseases e.g. type 1 diabetes, by using stem cells to replace the pancreatic cells that produce insulin.

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18
Q

What is meiosis?

A

Meiosis is reduction division in which the chromosome number is halved from diploid to haploid resulting in genetically different cells.

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19
Q

What provides the raw material for selection, and allows organisms to evolve in response to changing environments?

A

Gametes are genetically different from the parent cell. Fertilization is random and there are many possible combinations of genes so the fertilized diploid cells (zygote) produced are not genetically identical. This provides the raw material for selection and allows organisms to evolve in response to changing environments.

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20
Q

Describe the process of meiosis.

A

One pair of homologous chromosomes line up and are copied and then there are two divisions of the cell resulting in 4 gametes.

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21
Q

Where does meiosis occur (in humans and in plants)?

A

Meiosis occurs in the sex organs. In humans - the ovaries and testes, and in flowering plants in the anthers and in the ovules.

22
Q

The cells in the ______ and __________ are ______. After meiosis, the egg cell and sperm cells are produced each with a ________ nucleus (___ ____________). After fertilization, a ______ _____ (__ chromosomes) results.In sexual reproduction the number of chromosomes __________ ________ from __________ __ ____________.

A

The cells in the ovaries and testes are diploid. After meiosis, the egg cell and sperm cells are produced each with a haploid nucleus (23 chromosomes). After fertilization, a diploid zygote (46 chromosomes) results. In sexual reproduction, the number of chromosomes stays constant from generation to generation.

23
Q

What is inheritance?

A

Inheritance is the transmission of genetic information from generation to generation.

24
Q

What is monohybrid inheritance?

A

Monohybrid inheritance concerns the inheritance of a single characteristic, such as plant height or flower colour or gender of an organism. It involves the inheritance of the alleles of one gene.

25
Q

What is a genotype?

A

Genetic makeup of an organism in terms of the alleles present (e.g. Tt or GG).

26
Q

What is a phenotype?

A

The observable features of an organism (e.g. tall plant or green seed).

27
Q

What is meant by homozygous?

A

Has two identical alleles of a particular gene (e.g. TT or gg).

28
Q

What is meant by heterozygous?

A

Has two different alleles of a particular gene (e.g. Ttor Gg).

29
Q

What are two identical homozygous individuals that breed together?

A

This is pure breeding.

30
Q

Will heterozygous individuals be pure-breeding?

A

Heterozygoys individuals will not be pure-breeding.

31
Q

What is a dominant allele?

A

Is expressed if it is present in the genotype (eg T or G).

It will show up in the phenotype whether the organism is heterozygous Tt or homozygous TT.

32
Q

What is a recessive allele?

A

Is only expressed when there is no dominant allele of the gene present in the genotype (eg t or g).

It will only show up in the phenotype if the organism is homozygous tt.

33
Q

What is the use of a punnet square?

A

A Punnett square can be used to predict the possible combinations of alleles in the zygote.

34
Q

What do genetic diagrams show?

A

Genetic diagrams show the ratios expected in the offspring but not the actual numbers. Probabilities do not always match reality.

35
Q

What can test crosses be used to do?

A

Test crosses can be used to identify an unknown genotype.

36
Q

What is inheritance of sex in humans?

A

This is a special form of monohybrid inheritance.

37
Q

What are the human sex chromosomes?

A

The X and Y chromosomes are the sex chromosomes.

38
Q

What is co-dominance?

A

Co-dominance is a situation in which both alleles in heterozygous organsims contribute to the phenotype - neither is dominant or recessive to the other.

39
Q

What type of inheritance are blood groups?

A

Blood groups are an example of co-dominance.

40
Q

What are the alleles for human blood groups and which is dominant and which is recessive?

A

The human blood group has three alleles, ABO, given the symbols I*, and A and B alleles are co-dominant and I° is recessive.

41
Q

What are the genotypes for the following blood groups?
- Blood Group A.
- Blood Group B.
- Blood Group AB.
- Blood Group O.

A
  • Blood Group A = IAIA and IAIO
  • Blood Group B = IBIB and IBIO
  • Blood Group AB = IAIB
  • Blood Group O = IOIO.
42
Q

How can the human blood group be identified?

A

The human blood groups are easily detected by a simple test on a blood sample.

43
Q

What is a sex-linked characteristic?

A

Is a feature in which the gene responsible is located on a sex chromosome and this makes the characteristic more common in one sex than in the other.

44
Q

Is the Y chromosome shorter than the X chromosome?

A

The Y chromosome is much shorter than the X chromosome.

45
Q

What are sex-linked genes?

A

There are genes on each of these non-homologous chromosomes, that do not have a copy on the other chromosome.

46
Q

Does the man or the women carry the gene for colorblindness? Give a reason for you answer. Why can’t a man pass on the gene to his son?

A

The woman carries the gene as the X chromosome is longer. A man cannot pass it on to his son because the Y chromosome does not carry the colour-blind gene.

47
Q

What type of inheritance is colorblindness?

A

Colour blindness is an example of a sex-linkage.

48
Q

What are the genotypes for the following groups of people in regard to colorblindness:
- Normal female.
- Female carrier of colorblindness.
- Colour blind female.
- Normal male.
- Colorblind male.

A
  • Normal female = XBXB.
  • Female carrier of colorblindness = XBXb.
  • Colour blind female = XbXb.
  • Normal male = XBY
  • Colorblind male = XbY.
49
Q

What are chromosomes made of?

A

Chromosomes are made of DNA, which contain genetic information in the form of genes.

50
Q

What is a gene?

A

A gene is a length of DNA that codes for a protein.

51
Q

What is an allele?

A

An allele is an alternative form of a gene.

52
Q

What are the four structural points of DNA?

A
  • Two strands coiled together to form a double helix.
  • Each strand contains chemicals called bases.
  • Bonds between pairs of bases hold the strand together.
  • The bases always pair the same way (A with T and C with G).