inhalational Anesthetic Agents

Question 1

prevent response to supramaximal stimulus in 50% of patients at STP

Answer 1

Minimum alveolar concentration (MAC)

Question 2

Range:

Answer 2

Halothane (0.8-0.9)
Isoflurane (1.3 to 1.6)
Sevoflurane (2.3 -2.5)
Desflurane (7-10)

Question 3

Order of Potency

Answer 3

Methoxy > Halothane > Isoflurane > Enflurane > Sevoflurane > Desflurane > N2O

Question 4

Factors decreasing MAC

Answer 4

narcotics, sedative, analgesics, old age, hypothermia, hypotension, pregnancy (25-40%), severe hypoxemia, severe hypercapnia

Question 5

_______ is best for mask induction

Answer 5

Sevoflurane

Question 6

Second gas effect of N2O

Answer 6

it will accelerate initial uptake of an anesthetic gas given concomitantly

Question 7

CV effect of Halothane

Answer 7

arrythmogenic

Question 8

Compound A – sevoflurane degredation, occurs when

Answer 8

soda lime is dessicated or hot. Nephrotoxic in rats at high concentrations. Do not want to go below 2 L/min in O2 circle system

Question 9

Malignant Hyperthermia

Answer 9

life threatening myopathy. Genetic defect, triggered by halothane, but possible with all anesthetic gases. Typically in humans and pigs. Treat with dantrolene

Question 10

Halothane Hepatitis

Answer 10

hepatic necrosis and death. Immune mediated reaction, previous exposure to traces, rarely documented in animals

Question 11

part of the US department of Justice, issues license to clinics/hospitals for controlled drugs

Answer 11

• Administration

Question 12

Inproper or inaccurate drug keeping log

Answer 12

DEA may withdraw license to use controlled drugs, lead to investigation