Inflammation

Question 1

Major Acute Phase Proteins

Answer 1

a1-antitrypsin
a1-chymotrypsin
haptoglobin
ceruloplasmin
fibrinogen
C3, C reactive protein, hemopexin, serum amyloid protein

Question 2

a1-antitrypsin (AAT)

Answer 2

limit damage the proteolytic enzymes released by leukoctyes cause

Question 3

Haptoglobin and CRP

Answer 3

Collect, transport, and process cellular debris after necrosis

Question 4

Amyloid A Protein

Answer 4

High density lipoprotein
Stimulated by IL-1 released from macrophages
Prolonged inflammation caused amyloidosis (Congo red)

Question 5

CRP

Answer 5

Levels rise 4-6 hours after injury

Most useful APR to measure in Lab

Question 6

ESR

Answer 6

Erythrocyte Sedimentation Rate
Increased proteins in plasma increase rate
Rouleaux Formation

Question 7

Normal ESR

Answer 7

1-10 mm/hr Males

1-20 mm/hr Females

Question 8

Supporative Inflammation

Answer 8

Causes formation of Pus

Seen in Acute Appendicitis, Bronchopneumonia, Lung Abscesses, and Acute gangrenous cholecystitis

Question 9

Fibrinous Inflammation

Answer 9

Acute pleuritis
Gives bread and butter appearance
Common cause is lung infections

Question 10

Membranous inflammation

Answer 10

Pseudomembranous Colitis

Discrete yellow white patches on membrane of colon

Question 11

Allergic Inflammation

Answer 11

Occurs in nasal mucosae
Crosslinking of IgE on Mast Cells and Eosinophils
Development of nasal polyps

Question 12

What is often the cause of granulomatous inflammation

Answer 12

TB

Question 13

Pressure ulcers are typically associated with the presence of

Answer 13

Granulation Tissue (Vascularized for repair…not granuloma)