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Pathophysiology - FINAL > Inflammation > Flashcards

Inflammation Flashcards

1
Q
  • Innate immunity depends on?
A

Physical, mechanical, and biochemical barriers.

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2
Q
  • Innate immunity depends on?
A

Physical, mechanical, and biochemical barriers.

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3
Q
  • Innate immunity depends on?
A

Physical, mechanical, and biochemical barriers.

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4
Q
  • Innate immunity depends on?
A

Physical, mechanical, and biochemical barriers.

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5
Q
  • Systemic S/S of acute inflammation?
A

Fever (caused by IL-1), inflammatory markers increase risks of illness.

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6
Q
  • What is the inflammatory sequence?
A
  1. Arterial vasodilation
  2. Vasoconstriction
  3. Plastic leakage
  4. Edema
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7
Q
  • Inflammatory response promotes?
A

Healing

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8
Q
  • Systemic S/S of acute inflammation?
A

Fever (caused by IL-1)

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9
Q
  • What do interferons prevent?
A

Viruses from infecting healthy host cells.

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10
Q
  • Inflammatory response promotes?
A

Healing

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11
Q
  • Systemic S/S of acute inflammation?
A

Fever (caused by IL-1)

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12
Q
  • Chronic inflammation causes?
A

Lymphocytic & macrophilic infiltration

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13
Q
  • Histamine release stimulated by?
A

Mast cells

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14
Q
  • 1st WBC to enter site of inflammation?
A

Neutrophils

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15
Q
  • What are macrophages?
A

Phagocytic cells that engulf debris & activate adaptive immune system

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16
Q
  • What do Eosinophils do?
A

Anti-inflammatory cells that prevent parasitic infection

17
Q
  • What are platelets?
A

Clotting cascade to stop bleeding

17
Q
  • What are platelets?
A

Clotting cascade to stop bleeding

18
Q
  • Lymphocytes in the adaptive immune system?
A

Break up into T & B lymphocytes, T lymphocytes turn into natural killer cells

18
Q
  • Lymphocytes in the adaptive immune system?
A

Break up into T & B lymphocytes, T lymphocytes turn into natural killer cells

19
Q
  • What do natural killer cells do?
A

Recognize and eliminate infected cells and some cancer cells, link between innate and adaptive immune system

19
Q
  • What do natural killer cells do?
A

Recognize and eliminate infected cells and some cancer cells, link between innate and adaptive immune system

20
Q
  • What are monocytes?
A

Baby macrophages produced in bone marrow, migrate to inflammatory site, develop into macrophages

20
Q
  • What are monocytes?
A

Baby macrophages produced in bone marrow, migrate to inflammatory site, develop into macrophages

21
Q
  • What do cytokines do?
A

Increase bacterial effects of macrophages

22
Q
  • What are interleukins?
A

Produced by macrophages and lymphocytes in response to pathogen or stimulation of other products of inflammation

23
Q

What is IL-1 and what does it cause?

A

Pro-inflammatory, causes fever

24
Q

IL-6?

A

Pro-inflammatory

25
Q

IL-10?

A

Anti-inflammatory made my lymphocytes to down-regulate inflammatory response

Pathophysiology - FINAL (14 decks)

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