Infectologia

Question 1

qSOFA e definição de choque séptico

Answer 1

Question 2

SOFA

Answer 2

Question 3

SOFA

Answer 3

Question 4

Definição de Sepse

(SEPSIS-3)

Answer 4

Disfunção orgânica potencialmente fatal causada por uma resposta imune desregulada a uma infecção.

SEPSIS-3: Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection

Question 5

Definição de choque séptico

(SEPSIS-3)

Answer 5

Choque Séptico: sepse acompanhada por profundas anormalidades circulatórias e celulares/metabólicas capazes aumentar a mortalidade substancialmente

Septic shock is a subset of sepsis in which underlying circulatory and cellular/metabolic abnormalities are profound enough to substantially increase mortality.

Question 6

Critério para sepse

Answer 6

Sepse: suspeita ou certeza de infecção e um aumento agudo de ≥ 2 pontos no SOFA em resposta a uma infecção (representando disfunção orgânica)

Organ dysfunction can be identified as an acute change in total SOFA score 2 points consequent to the infection.

The baseline SOFA score can be assumed to be zero in patients not known to have preexisting organ dysfunction.

A SOFA score 2 reflects an overall mortality risk of approximately 10% in a general hospital population with suspected infection. Even patients presenting with modest dysfunction can deteriorate further, emphasizing the seriousness of this condition and the need for prompt and appropriate intervention, if not already being instituted.

Question 7

Critério para suspeita/identificação rápida da sepse

Answer 7

Patients with suspected infection who are likely to have a prolonged ICU stay or to die in the hospital can be promptly identified at the bedside with qSOFA, ie, alteration in mental status, systolic blood pressure 100 mm Hg, or respiratory rate 22/min.

Question 8

Critérios para choque séptico

Answer 8

Choque Séptico: sepse + necessidade de vasopressor para elevar a pressão arterial média acima de 65 mmHg e lactato > 2 mmol/L (18 mg/dL) após reanimação volêmica adequada

• Patients with septic shock can be identified with a clinical construct of sepsis with persisting hypotension requiring vasopressors to maintain MAP >= 65 mm Hg and having a serum lactate level >2 mmol/L (18 mg/dL) despite adequate volume resuscitation. With these criteria, hospital mortality is in excess of 40%.

Question 9

Fluxograma Sepse

Answer 9

Question 10

Fluxograma Sepse USP

Answer 10

Question 11

Sepsis 2 x Sepsis 3

Answer 11

Question 12

Lesões de pele na Endocardite

Answer 12

Question 13

Austrian syndrome

Answer 13

The triad of strep pneumoniae endocarditis, meningitis and pneumonia