Infective Endocarditis Flashcards
1
Q
Define
A
Colonisation/infection of endocardium( heart valves & chordae) by microbes forming bulky & variable vegetation(s).
2
Q
Aetiology
A
Blood borne organisms
Origin: poor dental hygiene, systemic sepsis, etc
3
Q
Contribute to Infection
A
Immunodeficiency
Malignancy
Diabetes
RHD
Catheter
Prosthetic valves
Degenerative calcific stenosis
4
Q
Pathogenesis
A
Vegetations -> embolise -> nailbed/retina hemorrhages, hypothenar swellings
Circulating immune complexes: GN, Vasculitis, arthritis
5
Q
Complications
A
Ring abscess Systemic embolisation Valve/chord rupture Septicaemia GN
6
Q
Duke criteria
A
2 major
1 major & 3 minor
5 minor
7
Q
Major clinical findings
A
Positive blood cultures
Echocardiographic findings
New valvular regurg
8
Q
Minor clinical findings
A
Predisposing Fever Vascular lesions Immunological phenomena Echo Culture
