Infectious Particles Flashcards

1
Q

What are viruses?

A

obligate intracellular parasites, can only replicate inside host cells

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2
Q

What are host cells?

A

include all groups of cellular organisms

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3
Q

What are virons?

A

viruses outside the host cell, inert infectious particles

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4
Q

each type of virus is essentially a piece of ___ enclosed in a ___, only one type of ___ is found in the iron of a given virus

A

nucleic acid/capsid/nucleic acid

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5
Q

___ viruses have 3 PRO, ___ viruses have >100 PRO

A

simple/complex

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6
Q

Hosts supply the ___ for viruses, as well as the ___ and ___ to reproduce

A

building blocks/machinery/energy

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7
Q

What are the parts that make up a viron?

A
  • envelope: lipid containing layer with embedded PRO
  • capsid: PRO coat around n.a.
  • nucleic acid
  • capsomeres: PRO subunit that makes up to capsid
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8
Q

What does the nucleocapsid refer to?

A

the capris and the nucleic acid

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9
Q

PRO in the envelope are ___ and encoded on the ___

A

virus-specific/viral genome

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10
Q

Shape is determined by:

A

the nature of capsomeres

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11
Q

Describe helical viruses

A

cylindrical, typical of plant viruses, spiral RNA core attached to identical capsomeres

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12
Q

Describe polyhedral viruses

A

several possible shapes, most common is the icosehedron (20 triangular faces), some contain more faces by having clusters of polyhedral on the surface (ex. HPV)

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13
Q

complex viruses are composed of ___ parts, the most complex are ___ which are made to infect ___

A

several/phages/bacteria

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14
Q

What are viroids?

A

closed single strand RNA circles, replication is dependant on host machinery, disease is caused when the viroid overtakes the host

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15
Q

What are some examples of viroid diseases?

A

cadang cadang, potato spindle tuber)

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16
Q

Where are prions?

A

only one PRO, cause neurological disease

17
Q

What are some examples of prion diseases?

A

mad cow, scrapie, CJD, VCJD, kuru

18
Q

___ prion PRO (PrPsc) induces misfolding of ___ PRO so prion does not replicate it, it includes an accumulation of misfolded PrPsc which ___ the cell, PrPsc is primarily found in ___

A

midfolded/PrPc/kills/neurons