Infectious Diseases

Question 1

Chronic granulomatous disease test

Answer 1

Dijudrorhodamine (DHR)- 123 fluorescence replaced the nitroblue tetrazolium test

Question 2

Orbital cellulitis vs preseptal cellulitis

Answer 2

Eyelid erythema and swelling
Chemosis need oral abx- preseptal

Orbital is all of above plus pain with EOM, proptosis, ophthalmoplegia with diplopia need IV Abx possible surgery

Question 3

Cervical adenitis organism and rx

Answer 3

Staph aureus and strep pyogenes
Usually affects the submandibular nodes
Lymph nodes are enlarged, tender, warm and red
Empiric abx for acute unateral lymphadenitis is clindamycin

Question 4

Sinusitis complication

Answer 4

Brain abscess
Headache, fever, early morning vomiting, green nasal discharge, pain in the face
Next step is urgent imaging- CT scan

Question 5

Serum sickness versus acute rheumatic fever

Answer 5

Serum sickness type three hypersensitivity reaction immune complex formation after antibiotics like penicillin or sulfa drugs 1 to 2 weeks after exposure fever polyarthralgia and or urticaria. Remove offending agent
A cute rheumatic fever is rare after appropriate antibiotic therapy rash is erythema marginatum

Question 6

Impetigo treatment for limited skin involvement?

Answer 6

Topical abx like mupirocin

IF extensive give oral abx like cephalexin, clinda or dicloxacillin