Hematology

Question 1

Chronic ITP what to do if patient is bleeding has thrombocytopenia refractory to pharmacologic interventions

Answer 1

Second line therapy why rituximab thrombopoietin agonist and splenectomy
Splenectomy removes the source of platelet disruption and is often curative and patience with ITP

Question 2

Eiram deficiency anemia versus thalassemia minor

Answer 2

Increased reticulocytes in thalassemia RDW normal

IDA has high RDW and low reticulocyte

Question 3

Factor eight deficiency (hemophilia A) Inhibitor development symptoms and why it develops?

Answer 3

Increased bleeding frequency or hemorrhage refractory to treatment program and PTT, but normal PT. Develops because immune system recognizes factor eight infusion as foreign

Question 4

Sickle cell trait anemia most likely cause of hematuria?

Answer 4

Renal papillary necrosis

Have a normal hemoglobin, RBC account, reticulocytes, negative crystals, intact RBCs on urinalysis

Question 5

Lead contamination screening test via arterial blood for definitive what to do?

Answer 5

Venous blood lead level samples to confirm the diagnosis