Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MRCP 1 > Infectious Diseases > Flashcards

Infectious Diseases Flashcards

1
Q 
Schizonts on blood film
Parasitaemia
Hypoglycaemia
Acidosis
Pyrexia
Severe anaemia
A

Falciparum malaria: features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Falciparum malaria: complications (5)

A 
Cerebral malaria
Acute renal failure
ARDS
Hypoglycaemia
DIC
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Falciparum malaria: Mx

A

IV artesunate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Non-falciparum malaria: causes

A

P. vivax
P. ovale
P. malariae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

P. vivax location

A

Central america and Indian subcontinent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

P. ovale location

A

Africa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

P. knowlesi location

A

South east asia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

fever, headache, splenomegaly

A

Non-falciparum malaria: features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

P. vivax / P. ovale features

A

Cyclical fever every 48 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

P. malariae features

A

Cyclical fever every 72 hours and nephrotic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Gram-positive cocci

A

Staphylococci

Streptococci

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Gram negative cocci

A

N. meningitides
N. gonorrhoeae
Moraxella catarrhalis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Gram positive rods

A 
ABCD L
Actinomyces
Bacillus anthracis
Clostridium
Diphtheria
Listeria
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Gram negative rods (6)

A 
E. coli
HiB
Pseudomonas
Salmonella
Shigella
Campylobacter
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Trypanosoma gambiense: location

A

West Africa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Trypanosoma rhodesiense: location

A

East Africa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Trypansoma chancre
Intermittent fever
Enlargement posterior cervical LN
CNS involvement

A

Sleeping sickness/African trypanosomiasis: features

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Trypansoma chancre: what?

A

painless SC nodule at site of infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Sleeping sickness/African trypanosomiasis: management

A

IV pentamidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Trypanosoma cruzi: location

A

America

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

American trypanosomiasis / Chagas: early features

A

Chagoma

Periorbital oedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

American trypanosomiasis / Chagas: late features

A

Dilated cardiomyopathy
Arrhythmias
Megaoesophagus / megacolon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

American trypanosomiasis / Chagas: Mx

A

Benznidazole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Chikungunya: what?

A

Alphavirus disease caused by mosquitoes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Chikungunya: where?

A

Africa, Asia and Indian subcontinent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Chikungunya: features

A

Severe joint pain
High fever
Flu like illness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Chlamydia: features

A

cervicitis, dysuria

urethral discharge

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Chlamydia: complications

A 
Epididymitis
PID
Endometritis
Infertility
Reactive arthritis
Perihepatitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Chlamydia: Ix

A

Nuclear acid amplification test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Chlamydia: Mx

A

Doxycycline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Gonorrhoea: features

A

Urethral discharge, dysuria
Cervicitis
Rectal and pharyngeal infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Gonorrhoea: Mx

A

IM ceftriaxone 1g

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Features of disseminated gonococcal infection

A

Tenosynovitis
Migratory polyarthritis
Dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Diphtheria: where?

A

Eastern Europe / Russia / Asia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Diphtheria: features

A

Sore throat with grey covering
Cervical LN
Neuritis
Heart block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Diphtheria: Mx

A

IM penicillin

Diphtheria antitoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Tellurite agar or Loefflers media

A

Diphtheria medium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Prolonged dysentry

A

Amoebiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Entamoeba histolytica causes..

A

Amoebiasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Amoebiasis: microscopy

A

Trophozoites if examinated within 15 minutes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Amoebiasis: Mx

A

Metronidazole

Luminal amoebicide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Cryptosporidiosis: features

A

Watery diarrhoea, abdominal cramps, fever, immunocompromise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Cryptosporidiosis: Ix

A

modified Ziehl-Neelsen stain

Red cysts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Cryptosporidiosis: Mx

A

Supportive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

PCP: features

A

Dyspnoea, dry cough, fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

PCP; stain

A

silver stain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

PCP; Mx

A

Co-trimoxazole

IV pentamidine in severe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Most common cause traveller’s diarrhoea

A

E coli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

E coli diarrhoea

A

Travellers
Watery stool
Abdo cramps and nausea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Giardiasis

A

Prolonged non-bloody diarrhoea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Cholera

A

Profuse watery diarrhoea

Severe dehydrations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Shigella

A

Bloody diarrhoea

Vomiting and abdo pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Staph aureus

A

Severe vomiting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

Campylobacter

A

Flu like prodrome
Crampy abdo pain, fever and diarrhoea
Complications inclide GBS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Bacillus cerus

A

Vomiting
Diarrhoea
Related to rice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

Borrelia burgdorferi causes

A

Lyme disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

Lyme disease; early features

A

Erythema migrans

Generally unwell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

Lyme disease; later features

A

Heart block, myocarditis

Neurological signs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Lyme disease: Ix

A

ELISA antibodies

Immunoblot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

Lyme disease: Mx

A

Doxycyline or amoxicillin

Ceftriazone in disemminated disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

Rickettsia ricketsii

A

Rocky mountain spotted fever

62
Q

Rocky mountain spotted fever: features

A

Headache and fever
Peripheral rash
Maculopapular - vasculitic

63
Q

Coxiella burnetti

A

Q fever

64
Q

Q fever

A

Pneumonia

65
Q

Rickettsia tyhpi

A

endemic typhus

66
Q

Endemic typhus

A

Central rash spreading peripherally

67
Q

Rickettsia prowazekii

A

Epidemic typhus

68
Q

Rickettsiae: gram stain

A

gram negative parasites

69
Q

Leishmania tropica

A

Cutaneous leishmaniasis

70
Q

Leishmania mexicana

A

Cutaneous leishmaniasis

71
Q

Cutaneous leishmaniasis

A

Crusted lesion

72
Q

Leishmania braziliensis

A

Mucocutaneous leishmaniasis

73
Q

Leishmania donovani

A

visceral leishmaniasis

74
Q

Visceral leishmaniasis: where

A

Mediterranean, Asia, S America, Africa

75
Q

Visceral leishmaniasis: features

A

Fevers, sweats, rigors,
HSM
Poor appetite
Gray skin

76
Q

Syphilis: VDRL

A

Negative after treatment

77
Q

Syphilis: TPHA

A

Positive following treatment

78
Q

Strep pyogenes

A

Erysipelas
Impetigo
Cellulitis
Necrotising facsciitis

79
Q

Chlaymydia trachomatis causes…

A

Lymphogranuloma venereum (LGV)

80
Q

LGV: RF

A

Men who have sex with men

HIV

81
Q

LGV: features

A

Painless ulcer
Inguinal lymphadenopathy
Proctocolitis

82
Q

LGV: Mx

A

Doxycyline

83
Q

Listeria: spread

A 
Contaminated food (dairy products)
Low temperatures
84
Q

Listeria: features

A

Diarrhoea, flu like illness
Pneumonia
Ataxia
Seizures

85
Q

Listeria: BC

A

‘tumbling motility’

86
Q

Listeria: Mx

A

Amoxicillin / ampicillin

87
Q

Listeria: pregnancy

A

miscarriage, premature labour, still birth, chorioamnionitis

88
Q

Brucellosis: where?

A

Middle East

89
Q

Brucellosis: who?

A

Farmers, vets and abattoir workers

90
Q

Brucellosis: features

A

Fever, malaise
HSM
Sacroiliitis

91
Q

Rose Bengal plate

A

brucellosis

92
Q

Brucellosis: Mx

A

Doxycycline and streptomycin

93
Q

Measles: prodrome

A

Irritable, conjunctivitis, fever

94
Q

What are koplick spots?

A

White spots on buccal mucosa

Sign of measles

95
Q

Measles: rash

A

Behind ears then to whole body

Maculopapular rash becoming blotchy and confluent

96
Q

Measles: complications

A

Otitis media
Pnuemonia
Encephalitis
Sclerosing panecephailitis

97
Q

Malaria prophylaxis: what is in malarone

A

Atovaquone and proguanil

98
Q

Atovaquone and proguanil: SE

A

GI upset

99
Q

Atovaquone and proguanil: Time before and after travel

A

1-2 days before

7 days after

100
Q

Chloroquine: SE and CI

A

Headaches

CI in epilepsy

101
Q

Chloroquine: administration

A

taken weekly

102
Q

Chloroquine: time before and after travel

A

1 week before

4 weeks after

103
Q

Doxycyline: SE

A

photosensitivity

oesophagitis

104
Q

Doxycycline: time before and after travel

A

1-2 days before

4 weeks after

105
Q

What is is lariam?

A

Mefloquine

106
Q

Mefloquine: SE

A

Dizziness

Neuropsychiatric

107
Q

Mefloquine: administration

A

taken weekly

108
Q

Mefloquine: time before and after

A

2-3 weeks before

4 weeks after

109
Q

HSV: ulcer

A

Fever

Multiple painful ulcers

110
Q

Syphilis: ulcer

A

painless ulcer

111
Q

Chancroid: ulcer

A

painful ulcer with painful inguinal LN

112
Q

HIV: ring enhancing lesions on CT

A

Toxoplasmosis

113
Q

Cerebral toxoplasmosis: Mx

A

Sulfadiazine

Pyrimethamine

114
Q

HIV: single brain lesions with homogenous enhancement

A

CNS lymphoma

115
Q

False positive cardiolipin test (6)

A 
Pregnancy 
SLE, anti-phospholipid syndrome
TB
Leprosy
Malaria
HIV
116
Q

What is Lemierre’s Sx?

A

Infectious thrombophlebitis of internal jugular vein

117
Q

Edes aegypti causes…

A

Dengue fever

118
Q

Dengue fever: features

A 
Retro-orbital headache
Fever
Myalgia
Pleuritic pain 
Facial flushing
Maculopapular rash
119
Q

Schistosomiasis: acute features

A 
Swimmer's itch
Fever
Urticaria
Arthralgia
Cough
Diarrhoea
Eosinophilia
120
Q

Schistosomiasis: chronic infection

A

RF for SCC

Bladder calcification

121
Q

Praziquantel treats..

A

chronic schistomiasis

122
Q

Pasteruella multocida

A

animal bites organism

123
Q

Animal bites: Rx

A

co-amoxiclav

124
Q

Bacteriostatic antibiotics (5)

A

Chloramphenicol, macrolides, tetracyclines, sulphonamides, trimethoprim

125
Q

Gardenerella vaginalis

A

BV

126
Q

BV: Rx

A

Metronidazole 5-7 days

127
Q

C. botulinum

A

Botulism

128
Q

Botulism: Rx

A

Botulism antitoxin and supportive care

129
Q

VZV in at risk groups

A

Check antibodies

Give VZIG

130
Q

Enteric fever: features

A 
Systemic upset
Bradycardia
Abdo pain, distension
Constipation
Rose spots
131
Q

Multiple keratinised genital warts

A

Topical podophyllum

132
Q

Single keratinised genital warts

A

Cryotherapy

133
Q

Leprosy Rx

A

Rifampicin, dapsone, clofazimine

134
Q

Melioidosis

A

South East Asia

DM

135
Q

Pubic lice: Mx

A

Topical treatment to entire body with reapplication 1/52 after

136
Q

Active TB: Rx

A

RIPE for 2/12

RI for 4/12

137
Q

Latent RB: Rx

A

RI for 3/12 OR

Isoniazid 6/12

138
Q

Lassa fever: source

A

Rats

139
Q

Anthrax: features

A

Painless black eschar
Oedema
GI bleeding

140
Q

Anthrax: Mx

A

Ciprofloxacin

141
Q

Aciclovir: MoA

A

Inhibits viral DNA polymerase

142
Q

Ganciclovir: MoA

A

Inhibits viral DNA polymerase

143
Q

Ribavirin: MoA

A

Interferes with the capping of viral mRNA

144
Q

Amantadine: MoA

A

Inhibits uncoating of virus in cell

Release dopamine from nerve endings

145
Q

Oseltamivir: MoA

A

Inhibits neuraminidase

146
Q

HIV: Seroconversion Features

A 
Sore throat
LN
Malasiase, arthraligia, myalgia
Diarrhoea
Maculopapular rash
Mouth ulcer
147
Q

HIV seroconversion: Diagnosis

A

HIV PCR and p24 antigen tests

148
Q

HIV: PEP

A

Oral antiretrovirals for 4/52

149
Q

Acute schistosmoiasis: features

A 
Fever
Urticaria
Arthralgia
Cough
Diarrhoea
Eosinophilia
150
Q

Chancroid: features

A

Painful genital ulcers

Unilateral, painful inguinal LN

151
Q

Live vaccinations (7)

A 
BCG
MMR
Influenza
Rotavirus
Polio
Yellow fever
Typhoid
152
Q

Yellow fever: progression

A

Flu –> remission –> jaundice and GI bleed

MRCP 1 (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions