Cardiology Flashcards
HOCM: what is it?
AD disorder causing diastolic dysfunction
HOCM: features
Exertional dyspnoea, angina, syncope, sudden death
HOCM: JVP
large a waves
HOCM: murmur
ejection systolic murmur
HOCM: associations
Friedreich’s ataxia, WPW
HOCM: echo
MR SAM ASH
Mitral regurgitation
Systolic anterior motion of anterior MV leaflet
Asymmetrical hypertrophy
HOCM: ECG
LVH, non-specific ST segment and T wave changes, deep Q waves
HOCM: Mx
ABCDE
Amiodarone, beta blockers, cardioverter defib, dual chamber pacemaker, endocarditis prophylaxis
HOCM: avoid
Nitrate, ACE-i, inotropes
Ebstein’s anomaly: what?
Low insertion of tricuspid valve resulting in large atrium and small ventricle
Ebstein’s anomaly: associations
Patent foramen ovale or ASD
WPW
Ebstein’s anomaly: features
Cyanosis, a wave, HSM, TR and RBBB
LAD: causes
Left anterior hemi block LBBB Inferior MI WPW Hyperkalaemia Congenital (ASD, tricuspid atresia)
RAD: causes
RVH Left posterior hemiblock Lateral MI Cor pulmonale PE ASD Normal in infants
S1 represents…
Closure of mitral and tricuspid valves
S2 represents…
Closure of aortic and pulmonary valves
S3 represents…
Diastolic filling of ventricle
S4 associations…
AS, HOCM, HTN
S4: ECG
p waves
S3: causes
LVF, constrictive pericarditis and MR
Loud S1 causes
MS, left to right shunts, short PR, hyperdynamic states
Quiet S1 causes
MR
Loud S2
Hypertension, hyperdynamic states, ASD
Soft S2
AS
Fixed split S2
ASD
Widely split S2
Deep inspiration, RBBB, pulmonary stenosis, severe MR
Pulmonary HTN: positive vasodilator testing
Oral CCB
Pulmonary HTN: negative vasodilator testing
Prostacyclin analogues - treprostinil, iloprost
Endothelin receptor antagonists - bosentan
Sildenafil
PR prolongation
MID RASH Myotonic dystrophia IHD/idiopathic Digoxin Rheumatic fever Aortic abscess Sarcoidosis Hypo K/Ca
DVLA: angioplasty
1 week off driving
DVLA: CABG
4 weeks off driving
DVLA: pacemaker insertion
1 week off driving
DVLA: ICD: ventricular arrhythmia
6 months no driving
DVLA: ICD: prophylactic
1 month off driving
DVLA: ICD
Permanent bar for group 2
Malignant HTN: Mx
IV sodium nitroprusside / labetolol
Aortic dissection: causes
MEN TSH Marfans Ehler Danlos Noonan's Trauma / Turners Syphilis HTN
Aortic dissection: Type A
Ascending aorta
Aortic dissection: type B
Descending aorta
Central acting antihypertensives (3)
Methyldopa
Moxonidine
Clonidine
TR; signs
Pan-systolic murmur
Giant v waves
Pulsatile hepatomegaly
L parasternal heave
TR; causes
RV infarction Pulmonary HTN Rheumatic HD IE Ebstein's Carcinoid's
Warfarin; major bleeding
Stop warfarin
IV vitamine K 5mg
PT complex
Warfarin; INR >8 and minor bleeding
Stop warfarin
IV vitamin K 1-3mg
Restart when INR <5
Warfarin; INR >8 and no bleeding
Stop warfarin
PO vitamin K 1-5mg
Restart when INR <5
Warfarin; INR 5-8, minor bleeding
Stop warfarin
IV vitamin K 1-3 mg
Restart when INR <5
Warfarin; INR 5-8, no bleeding
Withhold 1-2 doses
ECG: V1-4
Anteroseptal MI
ECG: Anteroseptal MI
LAD
ECG: II, III, aVF
Inferior MI
ECG: Inferior MI
Right coronary
ECG: V4-6, I, aVL
Anterolateral MI
ECG: Anterolateral MI
LAD or left circumflex
ECG: I, aVL, V5-6
Lateral MI
ECG: Lateral MI
Left circumflex
ECG: Tall R wave V1-2
Posterior MI
ECG: Posterior MI
Left circumflex
Ejection systolic murmur, louder on expiration
AS, HOCM
Ejection systolic murmur, louder on inspiration
PS, ASD
Ejection systolic murmur
ToF
Pansystolic murmur
MR, TR
VSD (harsh)
Late systolic murmur
Mitral prolapse
Coarctation
Early diastolic murmur
AR
Graham-Steel murmur (PR)
Mid-late diastolic murmur
MS
Austin-Flint murmur (AR)
Continuous machine like murmur
PDA
Takaysau’s arteritis: features
Features of vasculitis Unequal BP Carotid bruit Intermittent claudication AR
IE: poor prognostic factors
Staph
Prosthetic valve
Culture negative
Low complement levels
Decreased BNP
Obesity Diuretics ACEi BB ARBs Aldosterone antagonists
JVP: a wave
atrial contraction
JVP: x descent
ventricular systole
JVP: c wave
closure of tricuspid valve
JVP: v wave
passive filling of atria
JVP: y descent
opening of tricuspid valve
JVP: large a wave
TS, PS, pulmonary HTN
JVP: absent a wave
AF
JVP: cannon a waves
complete heart block, VT
JVP: giant v waves
TR
CHADSVASC
CHA2 DSV2 ASC CHF (1) HTN (1) Age >75 (2) Diabetes (1) Vascular - stroke/TIA (2) Age 65-74 (1) Sex (female) (1)
AR: features
Early Diastolic murmur
Collapsing pulse
WIde pulse pressure
AS: features
chest pain
dyspnoea
syncope
ESM
AS: severe features
Narrow pulse pressure Slow rising pulse Delayed ESM Soft S2 S4 LVH
AS: Mx asymptomatic
observe
AS: Mx symptomatic
valve replacement
AS: valvular gradient
> 40mmHg and with LVH then surgery
Arrythmogenic right ventricular cardiomyopathy: pathophysiology
AD
RV is replaced by fatty and fibrofatty tissue
Arrythmogenic right ventricular cardiomyopathy: ECG
Abnormalities in V1-3
Typically T wave inversion
Features suggestive of VT rather than SVT
AV dissociation Capture beats Positive QRS in chest leads LAD IHD Lack of response to adenosine or valsalva QRS >160ms
Brugada Sx: gene
Mutation in SCN5A gene
Encode myocardial sodium ion channel
Angina: Mx
1) BB or CBB
2) BB AND CBB
3) Long acting nitrate, ivabradine, nicorandil or ranlazine
Type A dissection: Mx
Surgical management
Target SBP 100-120
Typa B dissection: Mx
Conservative
Bed rest
BP control
BNP: effects
Vasodilator
Diuretic and natriuretic
Suppress sympathetic tone and RAAS
First cardiac enzyme to rise
Myglobin
Cardiac enzyme for re-infarctions
CK-MB
Hypokalaemia: ECG
U waves Small T waves Prolonged PR ST depression Long QT
NYHA Class 1
No Symptoms
No limitation
NYHA Class 2
Mild symptoms
Slight limitation of physical activity
NYHA Class 3
Moderate symptoms
Marked limitation of physicial activity
NYHA Class 4
Severe symptoms
Unable to carry out any physical activity
IE: Staph aureus
Most common cause
IE: Staph epidermis
Indwelling lines
Post 2 months valve replacement
IE: Strep viridans / sanguinis
Poor dentition
IE: Strep bovis
CRC
IE: Strep galloyticus
CRC
IE: Blind therapy
Native valve: amoxicillin/vanc +/- gent
Prosthetic valve: vanc, rifampicin + gent
Long QT: drugs
Amiodarone, sotalol TCA, SSRIs Methadone Chloroquine Erythromycin Haloperidol Ondansetron
MS: features
Mid late diastolic murmur
Loud S1
Low volume pulse
Malar flush
Direct thrombin inhibitors
Bivalirudin
Dabigatran
Treprostinil, iloprost MoA
Prostacyclin analogues
Bosentan, abrisentan
Endothelin receptor antagonists
Ticragelor SE
Dyspnoea
Right ventricular MI avoid..
Nitrates as reduces preload
COX inhibitors e.g.
Aspirin
P2Y12 Receptor blockers
Clopidogrel
GPIIb IIIa Inhibitors
Abciximab, tirofiban
Phosphodiesterase inhibitors
Dipyridamole
Drugs to maintain rhythm in AF
Sotalol, amiodarone and flecanide
AF: Factors favouring rate control
65+
History of IHD
AF: factors favouring rhythm control
Younger than 65 Symptomatic First presentation Lone AF Congestive HF
Atrial myxoma: location
Left atrium
Attached to fossa ovalis
Features suggestive of VT rather than SVT
AV dissocation Fusion / capture beats Positive QRS in chest leads Marked LAD History of IHD Lack of response to adenosine or valsala QRS >160
Acyanotic congenital heart disease
VSD ASD PDA Coarctation of aorta Aortic valve stenosis
Cyanotic heart disease
ToF
TGA
Tricuspid atresia
HOCM: poor prognosis
Syncope FH sudden death Young age Non sustained VT Abnormal BP changes on exercise
VSD: complications
AR IE Eisenmenger's RH failure Pulmonary HTN
Atrial Myxoma: location
Left atrium
Attached to fossa ovalis
Atrial Myxoma: features
Dyspnoea, fatigue, weight loss, pyrexia unknown origin, clubbing
Emboli
AF
Mid-diastolic murmur
Cholesterol Embolus: features
Eosinophilia
Purpura
Renal failure
Livedo reticularis
PDA: Mx
Indomethacin or ibuprofen
Pulsus paradoxus
Severe asthma, cardiac tamponade
Slow rising pulse
AS
Collapsing pulse
AR, PDA, hyperkinetic states
Pulsus alternans
Severe LVF
Syndrome X: what?
Angina like pain on exertion
ST depression of exercise stress test
Normal coronary angiogram