Infectious Disease Transmission/Hose Defense Flashcards
Prion
Protein particle w/o a genome.
Infectious and capable of producing disease
Mad cow
Slow neurodegenerative diseases
Virus
Intracellular pathogen
Must PENETRATE a susceptible living cell
Bacteria
Prokaryotes: autonomously replicating unicellular organisms.
Generally have no organelles
Gram positive color
Purple
Gram negative color
Red
Fungi
Consists of yeasts and molds
Free-living, eukaryotic
Arthropods
Parasite vector such as sicks, mosquitoes, flies
Ectoparasites
Parasites that infest external body surfaces and cause localized tissue damage.
Mites, chiggers, lice, fleas.
Protozoa
Single cell parasites that can cause disease.
Malaria, giradias
Helmiths
Collection of wormlike parasites
roundworms, tapeworms and flukes
Often involve multiple organ systems
Toxins are primarily produced by?
Bacteria
Exotoxin
Protein released during growth.
Enzymatically inhibit or modify key cellular components leading to death or dysfxn.
Diptheria, botulism, toxic shock syndrome
Endotoxins
Found in cell wall of gram negative bacteria
NOT actively released during growth
Potent activators of regulatory systems
Can induce shock, clotting, hypotension, fever
3 types of microbial attachment
Site specific (mucous, skin) Cell specific( T cell, resp. endo) Nonspecific (moist areas, charged surfaces)
Evasive factors
Polysaccharides protect microbe from phagocytic RBC's. Toxins that deplete host WBC's Blood clotting H Pylori neutralizes stomach acid Inactivation of IgA