Infectious Disease (guest lecturer)TEST 3 Flashcards
Epidemiology
study of distribution of determinants in population and application of these determinants to control health
In Sub Saharan Africa, what are the leading causes of death?
AIDS and Tuberculosis
Is HIV a disease or a pathogen?
Pathogen
AIDS?
Disease
Ro
The basic reproductive number: Average number of people an infected person can infect before they recover or die
Pathogen
org. that causes disease
Infection
replication of pathogens inside org
Disease
Change from normal phsyio to bad
If R0 is less than 1 what happens to the disease?
It dies out
If Ro is more than 1 what happens to disease
It persists
Equation for Ro?
infectious contact rateXduration of infection
Ro of sneezing on someone=
probability being sneezed on will lead to infectionXdays you are sneezing
What is the main thing to consider when looking at Ro?
The generation time of the infection!(time between getting infection and being able to infect someone else)
Reff
Reproductive number (consiers amount of people actually suseptible to the infection
If R0=4 how many people do we need vacinnated to stop the disease?
75% because of herd immunity (because we need 3/4 of infections to fail to get Ro=1)
If Ro=4 but Reff=2 how many people need to be vaccinated?
Only 50% because only half the population can get the disease (Reff) so that makes R0 basically 2 meaning we need 50% of the people who can get infections to be immunized to get R0=1
Latency Period
Time you have been infected but can not infect other people (this is super long time for HIV)
When infection preceeds disease what happens?
You can infect other people but you don’t even know you are sick because you don’t have symptons yet(AIDS)
SIR Model
a simple view of the world in terms of infectious disease:
Suseptibility (transmission) Infectious (recovery) Recovered
What effects Transmission Rate?
dependent on how many infected people are around you
B=
infectious contact rate
Transmision Viurlence Tradeoff
Good pathogens are good at spreading disease so they don’t want to killl the host
Vector
something that spreads a pathogen (like a mosquito)
Why does mosquito control work?
Because it shortens the days that mosquitos are alive an infectious and also shortens the number of days that they are infectious
Zoonotic Pathogens
Pathogens that come from animals
How did we discover origin of HIV?
By looking at the place with the most amount of HIV strains (the place with most diversity)