Infectious Disease Flashcards
White curd like vaginal discharge should make you think of what dx?
vaginal candida infection
Owl eye inclusion bodies should make you think of what dx?
cytomegalovirus (CMV)
If you have a pt with positive blood cultures for candida what is the first line drug?
amphotericin B
What is the tx for pertussis?
erythromycin x 7d
A leukemia pt has a CT scan of the liver which shows punched out lesions. What dx should you be thinking of?
Hepatosplenic candida
What disease does Rickettsia rickettsia cause?
Rocky Mountain spotted fever
An India ink stain showing cysts should make you think of what dx?
Cryptococcosis
A COPD pt has apical cavities and calcified nodes on his CXR. You also discover he has a pet bat and a few birds. What is the most likely dx?
Histoplasmosis
An HIV pt presents with a nonproductive cough and a CXR showing diffuse interstitial infiltrates. What is the most likely dx?
Pneumocystis jiroveci pneumonia
Honey and babies should make you think of what dx?
Botulism
What type of organism causes botulism?
A gram positive rod: clostridium botulinum
What is the treatment for botulism?
Antitoxin
A pt presents to the ER with acute progressive weakness, diplopia and a very dry mouth. What organism may be causing this?
Clostridium botulinum
Rice water stool should make you think of what dx?
Cholera
Is diphtheria a Gram positive or negative organism?
Gram positive
Gram positive vs gram negative
Despite their thicker peptidoglycan layer, Gram-positive bacteria are more receptive to antibiotics than Gram-negative, due to the absence of the outer membrane.
A stuck on grey membrane in the pharynx should make you think of what dx?
Diphtheria
What are 4 steps in dx’ing diphtheria?
Antitoxin
penicillin
remove membrane
report the case to CDC
What is the clinical name for whooping cough?
Pertussis
What type of organism causes tetanus?
A Gram + rod: clostridium tetani
A pt ate out last night and today has cramping and bloody diarrhea. What is the most likely organism?
Salmonella
Diarrhea with blood and mucus should make you think of what dx?
Shigella
What is the best test to dx malaria?
peripheral blood smear
What organism has been linked to reactive arthritis?
Shigella
also remember that reactive arthritis has a positive HLA-B27
What is the tx for shigella?
Bactrim or fluoroquinolones and hydration
What organism causes Lyme disease?
Borrelia burgdorferi
What is the minimum amount of time needed for a tick to transfer Lyme disease to a human?
24hrs
What is the drug of choice to tx Lyme disease in kids or pregnant women?
Amoxicillin
What is the drug of choice to treat C. difficile?
Metronidazole (Flagyl)
A pt was in the woods yesterday and today presents with erythema migrant. What is the most likely diagnosis?
Lyme disease
What drug is used for the treatment or prophylaxis of malaria?
Chloroquine
A pt was camping a few days ago and now has a rash that began on his wrists and ankles. What is the most likely diagnosis?
Rocky Mountain spotted fever
What is the drug of choice for treating Rocky Mountain spotted fever?
doxycycline
What is the drug of choice for the treatment of syphilis?
Penicillin
Any reference to dark field microscopy should make you think of what organism?
Trepenoma pallidum
Is staph gram positive or gram negative?
Gram positive
A pt being tx’ed for syphilis infection develops a fever, chills, muscle pain and headaches. Do you stop treatment?
No, this is Jarisch-Herxheimer reaction. The pt must be closely monitored, but it is a response to released endotoxin from the death of the spirochetes and not an allergic reaction.
What organism is believed to be the main culprit in creating peptic ulcers?
Helicobacter pylori
A painless, clean base chancre should make you think of what dx?
Primary syphilis
Is pseudomonas gram + or gram -?
Gram -