Infectious 2.1 gram positive Flashcards

1
Q

Staphylococcus aureus skin lesions

Affecting the hair follicle that may be solitary or multiple

A

Furuncles

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2
Q

Staphylococcus aureus skin lesions

Burrow into deeper tissue beneath subcutaneous tissue beneath subcutaneous tissue and rises again to form sinuses

A

Carbuncles

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3
Q

Inflammation of the apocrine glands usually found at the axilla

A

Hiradentis

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4
Q

Infection of the fingertips at the palmar sides

A

Pelons

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5
Q

Staphylococcus aureus skin lesions

Honey colored crusty lesions that may also be caused by streptococcus species

A

Impetigo “mamaso”

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6
Q

Desquamation or generalize exfoliation of the granulosa layer
Causes abscess, sepsis, osteomyelitis, pneumonia, endocarditis, food poisoning, toxic shock syndrome

A

SSSS or ritters disease

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7
Q

Associated with the use of tampons
Colonization of the S. Aureus
Causing hypotension and may be lethal

A

Toxic shock syndrome

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8
Q

Virulence factors

Receptor for fibrinogen, fibronectin, vitronectin functioning for attachment

A

Clumping factor

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9
Q

Virulence factors

Resisting phagocytosis

A

Capsule

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10
Q

Virulence factors

Digest the lipids in the CM

A

Lipase

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11
Q

Virulence factors

Binds the Fc portion of Ig inactivating antibody loss of antibody production function

A

Protein A

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12
Q

Virulence factors

Lyses membranes

A

Alpha
Beta
Delta toxin

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13
Q

Virulence factors

Specifically lyses membranes of RBC

A

Gamma toxin

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14
Q

Virulence factors

Specifically lyses membranes of WBC especially phagocytes

A

Leukocidin

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15
Q

Virulence factors

Causes bullous impetigo

A

Exfoliative A and B toxins

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16
Q

Virulence factors

Food poisoning and toxic shock syndrome using tampons

A

Super antigens

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17
Q

Resistant in all beta lactam antibiotics

A

Staph aureus

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18
Q

Part of normal flora of the skin

Opportunistic infections in catheterized patients

A

Staph epidermidis

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19
Q

UTI mostly in women

A

Staph Saprophyticus

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20
Q

Diffuse interstitial neutrophilic infiltrates with minimal destruction if host tissues

A

Strep

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21
Q

Streptococcus

Group A B hemolytic
With capsule
Flesh eating bacteria causing necrotizing fascitis
May also cause impetigo and toxic syndrome

A

Strep pyogenes

22
Q

Streptococcus

Due to M protein that stimulate antibodies

A

Rheumatic fever

23
Q

Streptococcus

Due to pyrogenic exotoxin
Circumolar pallor

A

Scarlet fever

24
Q

Streptococcus

Rapidly spreading erythematous cutaneous swelling
Butterfly rash at the bridge of the nose descending to the cheecks

A

Erysipelas

25
Streptococcus Group B beta hemolytic Causes chorichondrionitis in pregnant Sepsis and meningitis in neonates
Strep agalactiae
26
Virulence factor of strep agalactiae
Capsule
27
Streptococcus Lancet shaped in pairs Alpha hemolytic Causes community acquired pneumonia lobar and maningitis in adult
Strep pneumoniae
28
Strep pneumoniae virulence factors
Capsule | Pneumolysin
29
Streptococcus Alpha gamma hemolytic Normal oral flora Endocarditis
Strep viridans
30
Streptococcus Major cause of dental caries Metabolizes sucrose to lactic acid that produces demineralization of the enamel
Strep mutans
31
Causes endocarditis and urinary tract infection Low virulence Resistant to antibiotics
Enterococcus
32
Virulence factor of enterococcus
Capsule
33
Causes diphtheria | Life threatening syndrome that includes formation of a tough gray black pharyngeal membrane (pseudo membrane)
Corynebacterium dipheteriae
34
Toxin mediated damage to the nerves, heart, and liver | Causes fatty change and myofiber necrosis
Corynebacterium dipheteriae
35
Corynebacterium dipheteriae Virulence factors
Alpha and beta toxin Causes necrosis of epithelium and coagulation with exudates
36
Causes listeriosis Gram positive facultative intracellular bacillus Evokes an exudative pattern of inflammation with numerous neutrophils
Listeria monocytogenes
37
Listeria monocytogenes in pregnant women
Amionitis or amniochorionitis abortion and still birth
38
Listeria in neonates
Granulomatosis infantiseptica
39
Virulence factors of listeria monocytogenes
Internalins ( internalization of the microorganism) Listeriolysin O Phospholipase ACTA ( induces actin polymerization causing movement towards undirected cells)
40
Causes anthrax Acquires through exposure to animals or animal products Large, boxcar/bamboo fishing rod-shaped gram positive extracellular bacilli chains Spore former that can be used as biological warfare
Bacillus anthraxis
41
Bacillus anthraxis virulence factor Repeating units of D glutamic acid
Polyglutamyl capsule
42
Bacillus anthraxis virulence factor Active sub unit Edema factor or lethal factors resulting to interstitial edema or death of the cells, respectively
A subunit
43
Bacillus anthraxis virulence factor Protective antigen
B subunit
44
Types of anthrax Black eschar and regional lymphadenopathy
Cutaneous anthrax 95%
45
Types of anthrax Hemorrhagic mediastinitis (lymph nodes and lungs) Anthrax meningitis Rapidly leads to shock and death in 1-2 days
Inhalation anthrax
46
Types of anthrax Due to eating undercooked meat resulting to GI symptoms Abdominal pain, vomiting, bloody diarrhea
GI anthrax
47
``` Aerobic beaded slender bacteria Grow in distinctive branched chains resembling hyphae Fite-faraco stain Found in soil Causes opportunistinic infections ```
Nocardia
48
Nocardia Causing respiratory infections
Nocardia asteroides
49
Nocardia Causing infections of the skin
Nocardia baziliens
50
Gram positive cocci in clusters
Staphylococcus aureus