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Pathology Finals > Infectious 2.1 Gram Negative > Flashcards

Infectious 2.1 Gram Negative Flashcards

1
Q

Neisseria virulence factors

For attachment
Antigenic variations

A

Ova proteins and pili proteins

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2
Q

Neisseria

Causes bacterial meningitis in children

A

Neisseria menigitidis

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3
Q

Neisseria

Causes STD

A

Neisseria gonorrhea

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4
Q

Whooping cough

Laryngotracheobronchitis

A

Bortadella pertisis

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5
Q

Bortadella pertisis

Diagnosis

A

PCR

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6
Q

Bortadella pertusis. Virulence factor

Paralyses the cilia that loses the ability of clearance

A

Pertusis toxin

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7
Q

Opportunistic aerobic bacillus

Usual cause of nosocomial infections

A

Pseudomanos aeruginosa

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8
Q

External otitis (swimmer’s ears)
Pyocyanate and pyro verdin
Cystic fibrosis

A

Pseudomanos aeruginosa

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9
Q

Pseudomanos aeruginosa

Virulence factors

Produce sepsis

A

Endotoxins

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10
Q

Pseudomanos aeruginosa

Virulence factors

Mucoid exopolysaccharide

A

Alginate

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11
Q

Pseudomanos aeruginosa

Virulence factors

Inhibits protein synthesis

A

Exotoxin A

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12
Q

Pseudomanos aeruginosa

Virulence factors

Lyses red cells and degrades surfactants

A

Phospholipase C

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13
Q

Pseudomanos aeruginosa

Virulence factors

Degrades immunoglobulins

A

Elastase

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14
Q

Pseudomanos aeruginosa

Virulence factors

Toxic to endothelial cells, majority of the lesions may be found in the blood vessels

A

Iron containing compounds

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15
Q

Pseudomanos aeruginosa

Fleur del lire: flower like
Pale center and erythematous area

A

Necrotizing pneumonia

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16
Q

Pseudomanos aeruginosa

Inflammation of the endothelium with presence of the bacteria around the blood vessels

A

Pseudomonas vasculitis

17
Q

Pseudomanos aeruginosa

Due to bronchial obstruction

A

Bronchioectasis and pulmonary fibrosis

18
Q

Pseudomanos aeruginosa

Complication of bacteremia
Initially presents as microthrombi or presence of clots
Once the clots are degraded, bleeding the. Manifest late stage

A

Disseminated intravascular coagulopathy

19
Q

Pseudomanos aeruginosa

Well demarcated necrotic and hemorrhagic oval skin lesions

A

Echtyma grangrenosum

20
Q

Caused black death or plaque

A

Yersinia pestis

21
Q

Transmitted by flea bites (from infection or rodents to humans ) or by aerosols

A

Yersinia pestis

22
Q

Yersinia pestis

Causes lymph node enlargement (buboes)

A

Bubonic plaque

23
Q

Yersinia pestis

Severe broncho pneumoniae

A

Pneumonic plaque

24
Q

Yersinia pestis

Necrosis of lymph nodes
Bacteremia induces DIC

A

Septicemic plaque

25
Q

Causes soft chancre/chancroid
Sexual transmitted disease
Painful ulcerative infections of the genital areas and draining lymph nodes

A

Hemophilus ducreyi

26
Q

Elephantiasis

Causes ulcerations and develops extensive scarring or abundant granulation tissue

A

Klebsiella granulomatis

27
Q

Klebsiella granulomatis formerly called as

A

Calymmatobacterium donovani

28
Q

Klebsiella granulomatis

Presence of ________ in macrophages

A

Donovani bodies

29
Q

Neisseria virulence factors

Inhibits opsonization

A

Capsule

Pathology Finals (7 decks)

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