Infectious 2.1 Gram Negative Flashcards
Neisseria virulence factors
For attachment
Antigenic variations
Ova proteins and pili proteins
Neisseria
Causes bacterial meningitis in children
Neisseria menigitidis
Neisseria
Causes STD
Neisseria gonorrhea
Whooping cough
Laryngotracheobronchitis
Bortadella pertisis
Bortadella pertisis
Diagnosis
PCR
Bortadella pertusis. Virulence factor
Paralyses the cilia that loses the ability of clearance
Pertusis toxin
Opportunistic aerobic bacillus
Usual cause of nosocomial infections
Pseudomanos aeruginosa
External otitis (swimmer’s ears)
Pyocyanate and pyro verdin
Cystic fibrosis
Pseudomanos aeruginosa
Pseudomanos aeruginosa
Virulence factors
Produce sepsis
Endotoxins
Pseudomanos aeruginosa
Virulence factors
Mucoid exopolysaccharide
Alginate
Pseudomanos aeruginosa
Virulence factors
Inhibits protein synthesis
Exotoxin A
Pseudomanos aeruginosa
Virulence factors
Lyses red cells and degrades surfactants
Phospholipase C
Pseudomanos aeruginosa
Virulence factors
Degrades immunoglobulins
Elastase
Pseudomanos aeruginosa
Virulence factors
Toxic to endothelial cells, majority of the lesions may be found in the blood vessels
Iron containing compounds
Pseudomanos aeruginosa
Fleur del lire: flower like
Pale center and erythematous area
Necrotizing pneumonia
Pseudomanos aeruginosa
Inflammation of the endothelium with presence of the bacteria around the blood vessels
Pseudomonas vasculitis
Pseudomanos aeruginosa
Due to bronchial obstruction
Bronchioectasis and pulmonary fibrosis
Pseudomanos aeruginosa
Complication of bacteremia
Initially presents as microthrombi or presence of clots
Once the clots are degraded, bleeding the. Manifest late stage
Disseminated intravascular coagulopathy
Pseudomanos aeruginosa
Well demarcated necrotic and hemorrhagic oval skin lesions
Echtyma grangrenosum
Caused black death or plaque
Yersinia pestis
Transmitted by flea bites (from infection or rodents to humans ) or by aerosols
Yersinia pestis
Yersinia pestis
Causes lymph node enlargement (buboes)
Bubonic plaque
Yersinia pestis
Severe broncho pneumoniae
Pneumonic plaque
Yersinia pestis
Necrosis of lymph nodes
Bacteremia induces DIC
Septicemic plaque
Causes soft chancre/chancroid
Sexual transmitted disease
Painful ulcerative infections of the genital areas and draining lymph nodes
Hemophilus ducreyi
Elephantiasis
Causes ulcerations and develops extensive scarring or abundant granulation tissue
Klebsiella granulomatis
Klebsiella granulomatis formerly called as
Calymmatobacterium donovani
Klebsiella granulomatis
Presence of ________ in macrophages
Donovani bodies
Neisseria virulence factors
Inhibits opsonization
Capsule
