infections of GI Flashcards
oral infections
dental caries, gingivitis, necrotizing ulcerative gingivitis (trench mouth)
CC: streptococcus mutans, strep oralis
VF: biofilms
mumps
parotitis, gopher like swelling, swelling of reproductive organs, fever, tired
CC: mumps virus
VF: syncytia
Tx: self limiting, treated under MMR
gastritis
sharp pain from the abdomen, can lead to ulcers and dark bloody stools, can also lead to gastric carcinoma
CC: heliobacter pylori
VF: urease enzyme, makes ammonia when breaking down urea
Tx: amoxicillin, tet, flagyl, clarithromycin
reiter’s symdome
urethritis, conjunctivitis, arthritis (can’t pee, can’t see, can’t climb a tree)
from LPS in the body, treat with anti-inflammatory
Guillain-Barre syndrome
peripheral neuropathy (paralysis), from LPS in the PNS, treat with cortical steroids
salmonella
liked to dairy and raw poultry, watery diarrhea
CC: one of the many salmonellas (G-)
VF: invasive, can hide in cells and make it to blood for shock, gets to bones and causes osteomyelitis
Tx: if it becomes systemic, use ampicillin or Bactrim
typhoid fever
invasion of the spleen and liver and blood stream
has fever, abdominal rash, chills, and neurological symptoms
Tx: ampicillin or Bactrim
shigella
intense abdominal pain, vomiting, intense straining, causes hemolytic uremic syndrome when toxin enters bloodstream and gets to the kidneys
CC: shigella sonnei, s. flexneri, s. dysenteriae
VF: shiga toxin-inhibits protein synthesis, invasive
Tx: bactrim, ampicillin, azithromycin
EHEC
tie to hamburger meat, bloody diarrhea, HUS
VF: shiga toxin and effacing lesions
Dx: can’t use sorbitol for metabolism
Tx: nothing
EIEC
bloody (streaks and flecks) diarrhea with pus
VF: invasive
Dx: cannot use lactose for metabolism
Tx: supportive treatment
ETEC
traveler’s diarrhea, watery, transmitted by fomites (dirty glasses and ice)
VF: two toxins
Tx: self limiting
EPEC
profuse watery diarrhea, vomiting, infants and toddler and adults with poor immune systems
VF: pedestal formations
Tx: monitor and supportive
EAEC
chronic watery diarrhea common in young children and aids patients
VF: forms hook
Campylobacter jejuni
associated with cooked poultry, watery, vomiting, and severe abdominal pain
VF: 2 toxins
chance of Guillain-barre
Tx: rehydrate, if severe, erythromycin
clostridium difficile
superinfection, yellow mucus-y diarrhea, cramps, fever, after antibiotics
CC: G+
VF: two enterotoxins and spores
Complications: pseudomembranous colitis
Tx: discontinue the antibiotic, switch to flagyl, replacement therapy