antibiotics Flashcards

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1
Q

-cillins

A

CWS inhibiters, great on gram +, work on some gram -, longer names are stronger

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2
Q

carbepenen

A

CWS inhibiter, good beta lactam for gram -

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3
Q

imipenen

A

CWS inhibiter, beta lactam resistent to beta lactamase

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4
Q

ampicillin and amoxicillin

A

CWS inhibiter, have an extended spectra, used in many infections

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5
Q

single syllable -cillins

A

CWS, used against staph

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6
Q

vancomycin

A

CWS, works on almost all G+, but no G-, super powerful, do other stuff before this one

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7
Q

isoniazid and ethambutol

A

CWS, disrupts the “PPG” of the gram (na)

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8
Q

Pretomanid

A

CWS, used on tuberculosis only

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9
Q

bacitracin and polymyxin B

A

CWS, pore formers, work on simple gram + and -, neomycin can be added, only topical

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10
Q

daptomycin

A

CWS, gram +, works well on staphs

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11
Q

Chloramphenicol

A

PSI, 50s, kills everything including red blood cells, only in SEVERE cases

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12
Q

Lincomycin and Clindamycin

A

PSI, 50s, used for shock, can cause c. diff

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13
Q

Erythromycin and Azithromycin

A

PSI, 50s, macrolide family, works well on gram + and NA

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14
Q

Tetracycline, doxycycline, minocycline

A

PSI, 30s, from aureomycin, very broad spectrum but very high toxicity, not for kids, teratogenic

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15
Q

aminoglycosides

A

PSI, 30s, serious gram -, teratogenic, cannot be taken orally

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16
Q

synercid

A

PSI, 50s, synthetic, good for staphs, enterococcus, and strep

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17
Q

oxazalidones

A

PSI, 50s, Zyvox, last line of gram +

18
Q

sulfonamides

A

AM, mimics PBA so no folate, competitive inhibition, often used in conjugation with trimethoprim, not for pregnant women

19
Q

trimethoprim

A

AM, non-competitive, used in conjugation with sulfonamides, not for pregnant women

20
Q

Bactrim

A

AM, sulfa and trimethoprim, used for UTIs

21
Q

ciprofloxacin

A

RI, prophylaxis, very broad spectrum, before surgery

22
Q

norfloxacin

A

RI, gram + and -, UTIs

23
Q

levofloxacin

A

RI, STDs, skin infections, systemic infections

24
Q

rifampin

A

RI, gram + and -, tuberculosis, pneumonias, UTIs, gastroenteritis

25
Q

Acyclovir and valacyclovir

A

DNA viral inhibitor

26
Q

foscarnet

A

DNA viral inhibitor

27
Q

ribavirin

A

RNA viral inhibitor

28
Q

NRTIs

A

competitive inhibition, -vudine and -avir

29
Q

NNRTIs

A

non-competitive inhibition

30
Q

NtARTIs

A

-fovir

31
Q

zanamivir

A

AV, competitive inhibitor for influenza

32
Q

Interferons

A

AV, non-competitive for hepatitis

33
Q

clostrimazole and miconazole

A

AF, topical ointments, lowest grade

34
Q

ketoconazole

A

AF, topical and oral, middle grade

35
Q

fluconazole

A

AF, only for AIDs, gets to the CSF

36
Q

amphotericin B

A

AF, high toxicity, only if systemic

37
Q

quinine and artemisinin

A

AP, anti-malarial, plant based, replaces by two others with quin in the name

38
Q

metronidazole

A

AP, flagyl

39
Q

pyrantel pamoate

A

AH, pinworms, low power

40
Q

mebendazole and thiabendazole

A

AH, good on hookworm and other worms

41
Q

ivermectin

A

AH, good on worms as well as live, scabies, and rosacea