Infection - Quinolones Flashcards

1
Q

examples of quinolones

A
  • ciprofloxacin
  • delafloxacin
  • levofloxacin
  • moxifloxacin
  • ofloxacin
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2
Q

what can quinolones cause and need to be used in caution with?

A
  • lower seizure threshold avoid in epilepsy
  • psychotic disorders
  • tendon disorders
  • hypersen reactions
  • sunlight and UV radition lower exposure
  • impair driving
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3
Q

quinolones MHRA

A
  • tendinitis
  • small risk of aneuroysm and dissection
  • small heart valve quinolones
  • risk of suicidal thoughts and behaviour
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4
Q

what age is there a higher chance of quinolones + tendinitis

A
  • higher in 60+
  • stop and seek advice if suspected
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5
Q

quinolones + aneursym symptoms?

A

sudden onset severe abdominal chest and back pain

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6
Q

quinolones + small heart valve regurgitation symptoms

A
  • SoB
  • peripheral
  • new heart palpations
  • odema
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7
Q

cautions of quinolones?

A
  • QT prolongation
  • myasthenia gravis
  • arthropathy in children and teens
  • perforated tympanic membrane (ear)
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8
Q

interactions of quinolones

food and drugs

A
  • avoid dairy products + mineral fortified drinks = lower absorption
  • drugs that cause QT prolongation
  • lowers seizure threshold (NSAIDs and ibuprofen)
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