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INF > Infection - Fungal Infections > Flashcards

Infection - Fungal Infections Flashcards

1
Q

what is aspergillus?

A

a common mold (a type of fungus) that lives indoors and outdoors.

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2
Q

tx of aspergillus

A

voriconazole

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3
Q

what is cryptococcosis?

type of bacteria/fungi, transmission route and who is it commonly assoc

A
  • Cryptococcus = invasive fungus
  • transmitted via inhalation of spores
  • commonly associated = immunosuppressive individuals
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4
Q

symptoms of cryptococcosis?

A
  • fever
  • headache
  • malaise
  • photophobia
  • neck stiffness
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5
Q

what is tx of cryptococcosis?

A

amphotericin B

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6
Q

tx of vaginal thrush

1st, 2nd and alternative if resistant

A

1) clotrimazole
2) fluconazole
- if resistant = itraconazole

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7
Q

tx of oral thrush

if resistant tx

A
  • nystatin
  • miconazole
  • fluconazole
  • if resistant - itraconazole
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8
Q

tx of skin + nail infections

route and drugs

A

topical therapy then systemic therapy
- itraconazole
- terbinafine

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9
Q

what is tinea capitis an infection of ?

A

head

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10
Q

what is tinea corporis an infection of ?

A

body

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11
Q

what is tinea crusis an infection of ?

A

groin

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12
Q

what is tinea pedis an infection of ?

A

feet

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13
Q

what is tinea uriguium/longchontosis an infection of ?

A

nails

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14
Q

tinea (ringworm) tx

A

topical antifungal cream or terbinafine

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15
Q

duration of nail region terbinafine or amorofine nail laquer?

A

OW for 1 year

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16
Q

ringworm referral symptoms for GP

A

<18
2+ nails
diabetic
pregnant/BF

17
Q

antifungal medications

A
  • fluconazole
  • itraconazole
  • ketoconazole
  • voriconazole
18
Q

what do all antifungal infections cause?

A
  • QT prolongation
  • hepatotoxicity less in fluconazole
19
Q

what increases bioavailability of itraconazole?

A

carbonated drinks

20
Q

when is oral tx suspensed in ketoconazole?

A

life-threatening hepatotoxicity

21
Q

what occurs uncommonly with voriconazole?

A
  • phototoxicity
  • avoid sunlight exposure
22
Q

what condition is amphotericin B used in caution?

A

renal failure

23
Q

what is a risk of amphotericin B?

A
  • anaphylaxis risk with IV
  • test dose 30 min observation
24
Q

what is given as prophylaxis with amphotericin B?

A
  • prophylactic antipreyrics
  • hydrocortisone in pt with previous anaphylatic reactions
25
Q

what formulation of amphotericin B needs to maintained the same?

A
  • maintain same formulation between conventional, liposomal, lipid-complex formulation
  • serious harm and fatal overdose can occur
26
Q

what can terbinafine cause?

A

hepatotoxicity

INF (16 decks)

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