Infection & Immunity Flashcards

1
Q

What are pathogens?

A

Disease causing organism

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2
Q

What is the first barrier to pathogens?

A

Epithelia

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3
Q

What do the epithelia do when they come into contact with pathogens?

A

Produce cytokines and chemokines

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4
Q

What is the innate immune response?

A

Inbuilt immunity to resist infection.

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5
Q

What are the properties of the Innate immune response?

A

Non specific
No memory
Present from birth

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6
Q

What is the adaptive immunity response?

A

Immunity established to adapt to infection

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7
Q

What are the properties of the Adaptive immunity response?

A

Learnt by experience

Enhanced by second exposure due to memory

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8
Q

How is the importance of the innate immunity implied?

A

Rare to inherit deficiencies in innate immune mechanisms

Impairment of protection when deficiencies occur

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9
Q

What cells are involved in innate immunity?

A
Macrophage
Neutrophil
Eosinophil
Basophil
Mast cell
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10
Q

What is opsonisation?

A

Coating of a microorganism by antibodies to make it recognisable as foreign by phagocytes. So enhances phagocytosis

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11
Q

What coats bacteria to enhance opsonisation?

A

Fibronectin

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12
Q

What is the complement system?

A

Marks pathogens for destruction by covalently binding to their surface.

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13
Q

What are the cells of the Adaptive immune response?

A

T & B lymphocytes

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