Infection Flashcards
Immunogenicity
ability of pathogens to induce immune response
Pathogenicity/pathogen
ability to cause diseases; something that causes diseases
Toxigenicity
ability of certain microbes to produce toxins (endo/exo)
Virulence
severity of a disease
Chain of transmission
something that can be passed from one person to another: Infections agent, reservoir, portal of exit, mode of transmission, portal of entry, host, infectious agent
Infectious agent
some disease causing organism
reservoir
place where a pathogen lives and reproduces
portal of exit
how it gets out of the reservoir or infected patient
mode of transmission
mechanism by which the agent is spread
portal of entry
how the organism or agent gets into the host
host
any individual at risk for contracting the disease causing organism
Symbiosis relationship
benefits the human and no harm to microorganism
Mutualism relationship
benefit to both human and microorganism
Commensalism relationship
benefit only to microorganism but no harm done to human
pathogenicity relationship
benefits organism and harms human
Physical and mechanical barriers
epithelial cells constantly shutting or removing organisms to present a barrier, mucous membranes, coughing, sneezing, peeing, pooping, sweat, saliva, tears
adherence
helps microbes stick
invasion
how microbes get in
bacteria enzymes
wlil degrade tissue or dissolve WBC and RBC
antiphagocytic factors
microbes have outside coating that make it not recognizable to leukocytes; can help with adherence so hard to get rid of
endospores
ability to dorm an internal spore of resting state; resistant to heat and chemicals so when conditions are better they will reactivate and cause disease
mobility
some have ability to move away from repellents to increase likelihood of living
antimicrobial
mutation within microbe that allows it to survive in the presence of antibiotics; comes from overdose or sub theraputic use of antibiotics
bacteria
single cell organisms with rigid wall and no internal organelles