Hematology Flashcards
Anemia
any deficit of red blood cells
Relative anemia
normal total RBC mass with increased plasma volume (pregnancy)
Absolute anemia
decrease in number of RBC
What is one major function of red blood cells?
delivering oxygen to tissue through hemoglobin
What occurs in tissue hypoxia?
pain in muscle with exercise, altered mental status or dizziness d/t lack of oxygen in brain, increased respiratory rate, pallor
What are compensatory mechanisms?
SNS kicks in and sends epinephrine and norepinephrine to help out; tells heart to work harder, dilate capillaries, and increase HR
What is DPG?
Increases in RBC to help hemoglobin release oxygen easier
How does bone marrow help tissue hypoxia?
It is stimulated to produce more RBC’s
Identify a classification system for anemia
Decreased RBC - iron deficiency; lack of iron leads to lack of hemoglobin
What is the treatment of anemia targeted at?
the cause
Iron deficiency is the most common
nutritional deficiency in the world and most common cause of anemia
What is pica?
craving non-food or non-nutritive substances
When is iron deficiency common in children?
16 - 18 months because they are moving from iron fortified formula to solid foods and milk
Causes of thrombocytopenia
decreased platelet production and decreased platelet survival, splenic sequestration, platelet dilation
Risks of developing thrombi
Virchow’ triad: circulatory stasis, hypercoagulable conditions, epithelial injury