infection

Question 1

What bug causes lymphogrnuloma venerenum

Answer 1

chlamydia trachomatis serovars 1 - 3

Question 2

how often is pneumococcal vaccine repeated

Answer 2

5 yearly

Question 3

What is treatment for CMV encephalitis

Answer 3

ganicilovir

Question 4

What pathology is seen with pneumocystis jirovecii

Answer 4

elevated BDG levels

Question 5

What is the treatment for trichomonas vaginalis

Answer 5

metronidazole

Question 6

Can treponyma pallidium (syphillis) cause an AKI?

Answer 6

yes - acute glomerulonephritis

Question 7

What ABX should be px for chlamydia in pregnancy

Answer 7

azithromycin (not doxycycline tetracyclines)

Question 8

Given 2 x examples of inactivated vaccines

Answer 8

whopping cough, polio, rabies, hep A

Question 9

Does giardia cause bloody or non bloody diarrhoea

Answer 9

non bloody

Question 10

What are the symptoms of strongyloids stercoralis (threadworm)

Answer 10

eosinophili, dermatitis, local haemorrages (skin) and lung disease

Question 11

Does trachoma eye infection clamydia trachomatis affect one eye or both

Answer 11

both

Question 12

Why does dipheria toxin cause myocarditis

Answer 12

because of exotoxin

Question 13

What organism causes q fever and does it often grow in culture

Answer 13

coxiella burnetti. No not often cultured

Question 14

WHat is the cause of amoebic dysentery

Answer 14

entamoeba hystolitica causes bloody diarrhoea

Question 15

What disease is caused by cocksackie virus

Answer 15

hand foot and mouth disease (subtype virus 16 most responsible for outbreaks) however subtype 71 most associated with complications

Question 16

What is an AIDS defining illness with multiple raised purple lesion in someone with HIV and low CD4 count

Answer 16

Kaposi’s sarcoma

Question 17

What disease is cryoglobulinaemia most associated with

Answer 17

hepatitis C

Question 18

What is most common side effect of ribavirin

Answer 18

haemolytic anaemia

Question 19

What is treated with sulfasizide and promethasine

Answer 19

toxoplasmosis

Question 20

What is the most common opportunistic eye disease in the HIV positie population

Answer 20

CMV retinitis

Question 21

What cancers are associated with the EBV genome

Answer 21

gastric and nasopharyngeal cancer

Question 22

What presents with a black eschar

Answer 22

typhus infection

Question 23

How do you treat a needle stick injury in person with known Hep C infection

Answer 23

hep C RNA monthly surveillance

Question 24

What is mechanism of action of gentamicin

Answer 24

binds to ribosome sub unit

Question 25

what is mechanism of action of vancomycin

Answer 25

prevents synthesis of polymers for bacterial cell wall

Question 26

What abx causes oxidative damage to bacterial dna

Answer 26

metronidazole

Question 27

what inhibits reduction of dihydrofolate

Answer 27

trimethoprim

Question 28

what is the treatment for listeria meingitis

Answer 28

amipicillin

Question 29

What antibiotic is used in toxic shock syndrome

Answer 29

clinamycin

Question 30

what is the bacteria in BV

Answer 30

gardanella vaginalis

Question 31

HLA associated with behcet's

Answer 31

HLA B51

Question 32

what disease shows amastigotes in the bone marrow

Answer 32

leishmaniasis - treated with miltefosine

Question 33

WHen is CMV infection seen in patients with transplants

Answer 33

approx 6 weeks

Question 34

What bug causes cat scratch fever

Answer 34

bartonella henselae

Question 35

what HLA subtype is associated with hypersensitivity to hypercavir

Answer 35

HLA B5701

Question 36

what is the treatment for whipple's disease

Answer 36

ceftriaxone

Question 37

what are people post splenectomy most at risk of

Answer 37

n miningitidis, strep pneumoniae, and h influenzae

Question 38

What is tenea solium

Answer 38

Pork tapeworm Can cause cysticercosis

Question 39

How does a VIPoma present

Answer 39

Metabolic acidosis with normal anion gap Abdo pain dehydration watery diarrhoea

Question 40

Tx for entamoeba hystolytica

Answer 40

Metronidazole

Question 41

When does food poisoning with bacillus commence

Answer 41

6 hours after eating foods like rice

Question 42

Tx for giardia

Answer 42

Meteonidazole

Question 43

Bacillus incubation Food source Symptoms

Answer 43

7 hours Rice products N and v

Question 44

Campylobacter incubation period Food source

Answer 44

1 to 7 days Meat and dairy

Question 45

Staph aureus incubation Food source?

Answer 45

1 to 6 hours Dairy

Question 46

Ciclosporin MOA

Answer 46

IL-2 inhibition

Question 47

What is strongyloides ? How does it present ? Tx?

Answer 47

Helping infection Abdo pain diarrhoea and urticaria. Eosinophilia. Ivermectin.

Question 48

What category of drug os stavudine

Answer 48

NRTI

Question 49

What statin if preferred when taking NRTIs and protease inhibitors

Answer 49

Pravastatin Metabolism not as dependent on CYP450s as other statins

Question 50

Is GBS flaccid or spastic paralysis

Answer 50

Flaccid

Question 51

What HIV drug causes renal stones

Answer 51

Indinavir

Question 52

Side effects of zidovudine

Answer 52

Anaemia

Question 53

Side effects of zidovudine

Answer 53

Anaemia

Question 54

What causes chancroid

Answer 54

Haemophilus decreyi

Question 55

How does chancroid present

Answer 55

Tender ulcer with ragged edge Easily bleeds

Question 56

Is LGV painless or painful

Answer 56

Painless

Question 57

With what infection can sulphur granules be observed in anaerobic cultures

Answer 57

Actinomyces spp.

Question 58

Most common bug in platelets

Answer 58

Staph epidermis

Question 59

What is the disadvantage in quantifeton and mantoux and PCR of tb

Answer 59

May be positive in latent tb Doesn't necessarily correlate with active disease

Question 60

Tx lymphogranuloma venereum

Answer 60

Doxycycline

Question 61

Difference between syphilis and lgv in terms of lymphadenopathy

Answer 61

Syphilis lymphadenopathy takes 6 weeks to appear Lgv spreads rapidly to LNs Lgv doxy Syphilis pencillin v

Question 62

In vaccination which antibodies are positive

Answer 62

Anti HBs Hbcore antibodies are NEGATIVE there is no HBsAg

Question 63

Which antibodies are present in natural hep b infection

Answer 63

Both core and surface

Question 64

Tx for diphtheria

Answer 64

Azithromycin

Question 65

Name 3 x macrolides

Answer 65

Azithromycin Clarithromycin Erythromycin

Question 66

Tx for campylobacter

Answer 66

Macrolides ezythromycin

Question 67

where is bacillus cereus found?

Answer 67

rice

Question 68

what is erythema gratum repens associated with ?

Question 69

what type of pneumonia is most common in alcoholism

Answer 69

klebsiella pneumoniae > leads to cavitation

Question 70

name 3 x tnf inhibitor

Answer 70

adalimumab golimumab etanercept

Question 71

tx chlamydia in pregnancy

Answer 71

azithromycin 1g

Question 72

Tx for cyclospora

Answer 72

Co trimox

Question 73

Anti tpo graves or hasimotos

Answer 73

Hamishotos Graves thyroid stimulating hormone recepte

Question 74

What tests for measles

Answer 74

Immediately after rash rna 3 days after rash igM 7 -14 days after rash igG