Gastroenterology Flashcards

1
Q

What carcinoma is associated with PSC

A

Cholangiocarcinoma

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2
Q

Tumour associated with increased AFP

A

HCC

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3
Q

What metabolic component should be reduced in patient with alcoholism

A

protein - contains ammonia which could worsen encephalopathy

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4
Q

What describes the pathophysiology of haemochromatosis

A

decreased plasma hepcidin

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5
Q

What is the pathophysiology of WIlson’s disease?

A

Decreased plasma caerulopasmin

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6
Q

What drug can be given with pancreatic supplements in chronic pancreatitis to help improve efficiency of absorption

A

PPI

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7
Q

How is faecal calprotectin used

A

to differentiate between ibd and ibs

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8
Q

What antibody may be positive in both drug induced and autoimmune hepatitis?

A

anti LKM

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9
Q

what are the drug induced causes of hepatitis

A

Ketoconazole, isoniazid, methyldopa and nitrofurantoin

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10
Q

What antibody is associated with PBC

A

anti mitrochondrial AB

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11
Q

What antibody is associated with PSC

A

ANCA

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12
Q

Which one is associated with UC? PSC or PBC

A

PSC

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13
Q

cayses of transudative ascitic fluid protein <30g

A

cirrhosis, right sided cardiac failure, hypoalbuminaemia, acute nephritis and budd chiari

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14
Q

why does metformin cause diarrhoea

A

bile acid malabsorption

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15
Q

what is the incubation period of staph aureus food poisoning

A

2 - 4 hrs ( when contaminated by enterotoxin)

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16
Q

What is incubation period of salmonella

A

12-72hrs as organism invades mucosa

17
Q

In what type of food is yersina food poisoning found

A

uncooked meats

18
Q

what histology si found in whipple’s disease

A

Periodic acid schift macrophages infiltrating lamina propria

19
Q

What type of cancer is HNPCC associated with

A

endometrial cancer, glioblastoma, ovarian canacer

20
Q

What type of cancer is Familial polypolutus adenamatosis associated with

A

medulloblastoma

21
Q

What is treatment for tropical sprue

A

apicillin or tetracycline for 4 - 6 weeks

22
Q

What is a commonly registered side effect of ribavirin

A

haemolytic anaemia

23
Q

Commonest cause of SBP (bacteria)

A

e.coli

24
Q

what is improves outcomes in hepatic encephalopathy

A

rifaximin, neomycin

25
Q

complications of pseudoxanthoma elasticum

A

gi bleeding and mitrl valve prolapse

26
Q

side effect of pyryzinamide

A

joint pains

27
Q

is rifampacin an enzyme inhibitor or inducer

A

inducer

28
Q

are reticulocytes big or small

A

big

29
Q

What does d xylose absorption test for

A

Bacterial overgrowth syndrome

30
Q

treatment for severe/fulminant UC

A

ciclosporin

31
Q

what INR is CI to liver biopsy

A

greater than 1.6

32
Q

is ascites a CI to liver biopsy

A

yes

33
Q

hydrogen breath tests - for what?

A

bacterial overgrowth

34
Q

13C urea breath tests

A

h.pylori

35
Q
A