Gastroenterology Flashcards
What carcinoma is associated with PSC
Cholangiocarcinoma
Tumour associated with increased AFP
HCC
What metabolic component should be reduced in patient with alcoholism
protein - contains ammonia which could worsen encephalopathy
What describes the pathophysiology of haemochromatosis
decreased plasma hepcidin
What is the pathophysiology of WIlson’s disease?
Decreased plasma caerulopasmin
What drug can be given with pancreatic supplements in chronic pancreatitis to help improve efficiency of absorption
PPI
How is faecal calprotectin used
to differentiate between ibd and ibs
What antibody may be positive in both drug induced and autoimmune hepatitis?
anti LKM
what are the drug induced causes of hepatitis
Ketoconazole, isoniazid, methyldopa and nitrofurantoin
What antibody is associated with PBC
anti mitrochondrial AB
What antibody is associated with PSC
ANCA
Which one is associated with UC? PSC or PBC
PSC
cayses of transudative ascitic fluid protein <30g
cirrhosis, right sided cardiac failure, hypoalbuminaemia, acute nephritis and budd chiari
why does metformin cause diarrhoea
bile acid malabsorption
what is the incubation period of staph aureus food poisoning
2 - 4 hrs ( when contaminated by enterotoxin)
What is incubation period of salmonella
12-72hrs as organism invades mucosa
In what type of food is yersina food poisoning found
uncooked meats
what histology si found in whipple’s disease
Periodic acid schift macrophages infiltrating lamina propria
What type of cancer is HNPCC associated with
endometrial cancer, glioblastoma, ovarian canacer
What type of cancer is Familial polypolutus adenamatosis associated with
medulloblastoma
What is treatment for tropical sprue
apicillin or tetracycline for 4 - 6 weeks
What is a commonly registered side effect of ribavirin
haemolytic anaemia
Commonest cause of SBP (bacteria)
e.coli
what is improves outcomes in hepatic encephalopathy
rifaximin, neomycin
