Important genes of embryogenesis Flashcards
1
Q
Produced at the base of limbs in zones of polarizing activity
A
Sonic Hedgehog gene
2
Q
Involved in patterning along anterior-posterior axis
A
Sonic Hedgehog gene
3
Q
Involved in CNS Development; mutation can cause holoprosencephaly
A
Sonic Hedgehog gene
4
Q
Produced at apical ectodermal ridge (thickened ectoderm at distal end of each developing limb)
A
Wnt-7
5
Q
Necessary for proper organization along dorsal-ventral axis
A
Wnt-7
6
Q
Produced at apical ectodermal ridge. Stimulates mitosis of underlying mesoderm, providing for lengthening of limbs.
A
FGF gene
7
Q
Involved in segmental organization of embryo in craniocaudal direction.
A
Homeobox
8
Q
Mutations of this gene lead to appendages in the wrong locations
A
Hox
