immunosuppressants

Question 1

Drugs that block T-cell activation by preventing IL-2 transcription

Answer 1

Cyclosporine (Cyclophilin), Tacrolimus (FK506)

Question 2

Blocks B and T cell action by preventing response to IL-2

Answer 2

Sirolimus (Rapamycin)

Question 3

Blocks IL-2R

Answer 3

Basiliximab

Question 4

precursor drug that blocks nucleotide synthesis

Answer 4

Azathioprine

Question 5

Prevents purine synthesis in B and T cells

Answer 5

Mycophenolate Mofetil

Question 6

Inhibit NF-kappa light chain activator of B cells.

Answer 6

Glucocorticoids