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MTAP 1 > IMMUNOSEROLOGY > Flashcards

IMMUNOSEROLOGY Flashcards

1
Q

Predominant Ig in healthy human serum – this antibody has longest circulation life

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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2
Q

Predominant Antibody in the secondary/anamnestic secondary response

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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3
Q

Provides immunity to the newborn

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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4
Q

the only antibody that can cross the PLACENTA

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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5
Q

Only___________ can actively cross the placenta

A

IgG1 and IgG3

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6
Q

Most potent to least potent IgG

A

IgG 3, IgG 1, IgG 2

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7
Q

BEST PRECIPITATING ANTIBODY

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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8
Q

Small size antibody – can diffuse semi-solid medium

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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9
Q

Considered as warm reacting antibody
Can optimally react @ 37°C

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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10
Q

Always considered as clinically significant.

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

E

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11
Q

Considered as the biggest antibody – pentameric antibody (5 monomers)

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

D

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12
Q

Predominant antibody in the primary immune response and in the acute stage of disease

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

D

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13
Q

First to appear phylogeny and last to leave in senescence

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

D

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14
Q

It has J chain

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

A and D

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15
Q

Cold reacting antibody
Optimal temperature is 4°C

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

D

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16
Q

Most potent antibody that can fix complement protein

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

D

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17
Q

Considered as the BEST AGGLUTINATING ANTIBODY

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

D

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18
Q

First antibody to be expressed on the surface of B cells, because the Mu heavy chain is the First heavy chain to be synthesized in the B
cells

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

D

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19
Q

Exist as MONOMER and DIMER; It has 2 forms

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

A

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20
Q

Responsible for mucosal immunity against microbial agent that enters the body through mucosa/skin

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

A

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21
Q

The only antibody with secretory component

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

A

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22
Q

Can also be transferred from mother to the baby through the colostrum (breast milk)

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

A

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23
Q

Function is still unknown but believes to play a role in immunoglobulin

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

C

24
Q

Found on the surface of B-lymphocytes

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

C

25
Q

Second antibody to be displayed on the surface of B-cells; second to IgM

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

C

26
Q

Postulated to be an anti-idiotypic antibody

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

C

27
Q

Can attack the variable region

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

C

28
Q

Least abundant antibody Ig in the serum

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

B

29
Q

Heat-labile antibody, originally known as Reaginic antibody

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

B

30
Q

Only antibody that can binds strongly to mast cell and basophil receptor – the only antibody with specific receptor

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

B

31
Q

Mediates some types of hypersensitivity reactions

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

B

32
Q

The release of the histamine is due to the binding of IgE with an attached allergen

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

B

33
Q

Increased in parasitic infection and helminth infection

a. IgA
b. IgE
c. IgD
d. IgM
e. IgG

A

B

34
Q

Also known as anaphylactic hypersensitivity

A

Type 1

35
Q

Also known as antibody-mediated cytotoxic

A

Type 2

36
Q

Also known as complex-mediated

A

Type 3

37
Q

Also known as cell-mediated

A

Type 4

38
Q

Wheal and flare skin (uticaria and hives)
What type of hypersensitivity?

A

1

39
Q

hay fever, allergic asthma, hives and systemic anaphylaxis
What type of hypersensitivity?

A

1

40
Q

2 major phases of type 1 hypersensitivity

A

sensitization and activation

41
Q

Myasthenia gravis
What type of hypersensitivity?

A

2

42
Q

Grave’s disease
What type of hypersensitivity?

A

2

43
Q

Good pasture syndrome
What type of hypersensitivity?

A

2

44
Q

Hashimoto’s disease
What type of hypersensitivity?

A

2

45
Q

DM
What type of hypersensitivity?

A

2

46
Q

Transfusion reactions, HDN, AHA, Cold agglutinins
What type of hypersensitivity?

A

2

47
Q

SLE , RA
What type of hypersensitivity?

A

3

48
Q

Arthus reaction and serum sickness
What type of hypersensitivity?

A

3

49
Q

Contact dermatitis
What type of hypersensitivity?

A

4

50
Q

Hypersensitivity pneumonitis
What type of hypersensitivity?

A

4

51
Q

Pathogens in type IV

A

M. tuberculosis
M. leprae
P. carinii
Leishmania
Herpes

52
Q

Preferred method in type I

A

skin prick

53
Q

most common form of atopy or allergy

A

rhinitis

54
Q

principal effector cells of immediate hypersensitivity

A

mast cells

55
Q

gold standard in type IV-contact dermatitis

A

patch test

MTAP 1 (10 decks)

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