Immunopharmacology Flashcards
REVERSE
Cyclosporine
Cyclophilin is
REVERSE
- Monoclonal AB
- Antiplatelet antagonist of IIb/IIIa receptors
Abciximab used for
REVERSE
- Hep B and C
- Leukemia
- Melanoma
Interferon-Alpha used for
REVERSE
MS
Interferon-Beta used for
REVERSE
- Monoclonal AB
- RA and Crohns disease becaue it binds to TNF
Infliximab used for
REVERSE
- Monoclonal AB
- Kidney transplants by blcking IL-2 receptors
Daclizumab used for
REVERSE
- Monoclonal AB
- Non-Hodgkin lymphoma by binding to Surface protein
Rituximab used for
REVERSE
Immunosuppressant converted to 6-mercaptopurine
Azathioprine is
REVERSE
Chronic Granulomatous Disease by Increasing TNF
Interferon-Gama used for
REVERSE
- Monoclonal AB
- Kidney transplant by blocking Allograph rejection
Muromonab used for
REVERSE
Same as Cyclosporine
Tacrolimus mechanism of action
REVERSE
- Monoclonal AB
- Breast cancer because it is antagonist to ERB-B2 (Her 2/neu)
Trastuzumab used for
REVERSE
- Monoclonal AB
- RSV by blocking RSV protein
Palivizumab used for
REVERSE
Bind to clyclophilin or FK-binding protein causing decrease calcineurin and decrease activation of T-cell transcription factors leading to decrease in IL-2, IL-3 and IFgama
Cyclosporine mechanism of action