Immunology Part V

Question 1

What transcription factor goes to work after a naive CD4+ T cell receives instruction in the form of IL-2 and TGF-beta?

Answer 1

FOXP3

Treg cells!

Question 2

After measles exposure when should you give MMR vaccine and when should you give IgG?

Answer 2

72 hours after exposure, less than 6 days = give IgG
–Must wait 3-5 months after IgG before giving MMR to an unvaccinated child (otherwise vaccine is bound by IgG and body does not develop immune response)