Downing Part I

Question 1

Plasma clots, Serum. . .

Answer 1

does not!

Question 2

Rouloux or stacked red blood cells appear in. . .

Answer 2

. . .multiple myeloma!

Question 3

What percentage of the differential count is neutrophils?

Answer 3

50-70%

Question 4

What cell helps combat parasites/worms?

Answer 4

Eosinophils

• Bilobed
• Red tint

Question 5

What are eosinophils involved in?

Answer 5

Migrate to sites of allergic reactions (hay fever & asthma), inflammatory reactions, or parasitic worm invasions

Question 6

What do azurophilic granules act similar to?

Answer 6

Lysosomes!

Question 7

What are the functions of basophils (have very large, dark granules and two lobes)?

Answer 7

• Involved in initiating allergic and inflammatory responses (similar to mast cells)
• Fc receptors for the Fc fragment of IgE
• Release histamine
• Produce leukotrienes
• Similar effects to that of histamine, but actions are slower and more persistent

Question 8

What percentage of circulating lymphocytes are B and T?

Answer 8

B - 15%

T - 80-90%

Question 9

What does the nucleus in monocytes look like?

Answer 9

Indented, oval, kidney or horseshoe shaped (one lobe only!)

Question 10

What is important about monocytes?

Answer 10

1. Differentiate into macrophages in the connective tissues and other places
2. 2nd line of defense against invading organisms

Question 11

What percentage of the differential are lymphocytes?

Answer 11

20-40%

Question 12

What do promyelocytes have that other developing cells don’t?

Answer 12

Very large, uncondensed nucleus with nucleoli AND granules present!