Immunology/Allergy

Question 1

What tye of inflammatory response is asthma

Answer 1

Type 2

Th2 led –> IL4, IL5, IL13 activation

Question 2

Mechanism of action of T2 Inflammation in asthma

Answer 2

1) IL4 - Promotes B cells to produce IgE
2) IL5 - activates and promotes eosinophil growth
3) IL13 - Airway remodelling, mucous membrane hypersecretion

Question 3

C1 complement deficiency is assosciated with?

Answer 3

SLE

Question 4

C3 Complement deficinecy increases the risk of what?

Answer 4

Bacterial infections - Encapsulated bacteria such as - H.Ib, S.Pneumoniae, N.Meningitidis, E.Coli

Question 5

C5-9 Complement deficiency increases the risk of?

Answer 5

Recurrent meningitis