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Ophthalmology > Immunology > Flashcards

Immunology Flashcards

1
Q

What acts as an “anti-adhesive” in the eye?

A
  • mucous layer
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2
Q

What are some chemical properties of the eye immunology?

A
  • lysozyme
  • lactoferrin
  • transferrin
  • tear lipids
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3
Q

What attracts neutrophils?

A
  • chemotaxis
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4
Q

What is the principle antigen presenting cell for the external eye?

A

-Langerhans cells

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5
Q

Where are langerhan cells abundant in the eye?

A
  • cornea-scleral limbus
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6
Q

What is the only part of the eye with lymphatic drainage?

A
  • conjunctiva
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7
Q

What is a specialised lymphoid tissue found in the conjunctiva?

A
  • MALT
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8
Q

What is found at the peripheral cornea?

A
  • Langerhans cells
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9
Q

What is found immunological wise in the lacrimal drainage system?

A
  • MALT
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10
Q

What is immune privilege?

A
  • accommodation of antigens without eliciting an inflammatory response
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11
Q

What causes immune privilege in the eye?

A
  • blood-ocular barrier

- lack of direct lymphatic drainage

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12
Q

What is sympathetic ophthalmia?

A
  • injury in one eye can cause damage to both

- autoimmune reaction to occular antigens during trauma

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13
Q

What is the primary mediator in sympathetic ophthalmia?

A
  • T cells
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14
Q

Name an ophthalmic condition where it is a type I hypersensitivity reaction

A
  • acute allergic conjunctivitis
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15
Q

Define chemosis?

A
  • oedema of the conjunctiva

- linked to acute allergic conjunctivitis

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16
Q

Name a Type II hypersensitivity ophthalmic condition?

A
  • ocular cicatricial pemphigoid
17
Q

Name a type III ophthalmic hypersensitivity condition?

A
  • autoimmune corneal melting
18
Q

Name a type IV hypersensitivity ophthalmic condition?

A
  • corneal graft rejection
19
Q

Why is a corneal replacement generally well tolerated?

A
  • uses immune privilege
  • cornea lacks blood and lymph supply
  • central cornea is deficient in Langerhans cells

Ophthalmology (7 decks)

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