Immunology

Question 1

4 types of Hypersensitvity Rxns

Answer 1

1. Anaphylatic & Atopic
2. Direct Ig mediated (cytotoxic)
3. Immune Complex
4. Delayed

Question 2

Type I Hypersensitivity Rxn

Answer 2

=Anaphylactic & Atopic- FAST
Mech:
Free antigen cross-linked IgE on presensitized mast
cell & basophils –> release of vasoactive amines for
postcapillary venules (histamine)
–> delayed response: production of arachidonic acid
metabolites (leukotrienes)
Test: Skin test for specific IgE