Immunology Flashcards
Name the associated HLA allele: Hemochromatosis
A3
Name the associated HLA allele: Psoriatic arthritis
B27
Name the associated HLA allele: Ankylosing spondylitis
B27
Name the associated HLA allele: Inflammatory Bowel Disease
B27
Name the associated HLA allele: Reactive arthritis (Reiter Syndrome)
B27
Name the associated HLA allele: Celiac Disease
DQ2/DQ8
Name the associated HLA allele: Multiple sclerosis
DR2
Name the associated HLA allele: SLE
DR2, DR3
Name the associated HLA allele: Goodpasture Syndrome
DR2
Name the associated HLA allele: DM Type I
DR3, DR4
Name the associated HLA allele: Graves Disease
DR3
Name the associated HLA allele: Hashimoto Thyroiditis
DR3, DR5
Name the associated HLA allele: Rheumatoid arthritis
DR4
Name the associated HLA allele: Pernicious anemia
DR5
Which stimulus promotes differentiation of an undifferentiated Th cell into a Th1 cell?
IL-12
Which stimulus promotes differentiation of an undifferentiated Th cell into a Th2 cell?
IL-4
Which stimulus promotes differentiation of an undifferentiated Th cell into a Th17 cell?
TGF-Beta, IL-6
AIRE plays a key role in ______ selection in the thymus.
Negative
Name the stimulus for Th1 cell activation.
IFN-gamma, IL-12
Name the stimulus for Th2 cell activation.
IL-4
What is secreted by Th1 cells?
IFN-gamma
What is secreted by Th2 cells?
IL-4, IL-5, IL-10, IL-13
What is secreted by macrophages?
IL-12
What proteins are released by CTLs when they stimulate apoptosis in infected cells?
Perforin, Granzyme
