Immunology

Question 1

Mast Cells

Answer 1

found in connective/subcut tissues
basophilic
storage granules –> lytic enzymes (tryptase) + inflam mediators

Ig-E mediated degranulation triggers: injury, drugs, complement activation, foreign material

anaphylaxis when re-exposed to previously sensitised antigen

Question 2

Inflammatory Mediators

Answer 2

Histamine
Heparin
5-tryptase hydroxytrytamin (5-HT)
Leukotrienes
Platelet aggregating factor
Leukocyte chemotactic factor
Hyaluroindase