immunology 3 Flashcards
how do B cells recognise free organic antigens?
via BCR (surface Igm)
how do the secondary responses differ from the primary immune response in memory cells?
more rapid, larger, often qualitatively different
what is natural active immunity?
occurs during infection. Lymphocytes are activated by antigens on pathogen’s surface
what is artificial active immunity
injecting or taking antigens by mouth, takes time for T and B cells to be activated bu gives long lasting immunity
what is natural passive immunity?
mother to child through placenta or milk
What is artificial passive immunity?
used during potentially fatal diseases. Provides instant response but only temporary as antibodies are not the bodies own so memory cells are not created
what do B cells mature into?
Plasma cells
what are plasma cells responsible for
antibody production
what is the antigen receptor for the B cell called
surface immunoglobin
what are the intricate protruding shapes on the surface of antigens called?
epitopes
what are the two regions of the heavy chains of an antibody?
- constant region
- variable region
what are the 5 different classes of antibody?
IgM IgG IgA IgE IgD
Which MHC binds to peptides on the antigen and presents them to CD4 T cells ( the ones that activate B cells and macrophages)
MHC II
Which MHC binds to peptides on the antigen and presents them to CD8 tells (cytotoxic t cells)
MHC I
