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SEM2 - I/S > Immunology 3 > Flashcards

Immunology 3 Flashcards

1
Q

found on surface of Dane particle

A

HBsAg

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2
Q

foundin the body fluids of patients with HBV

A

hbsag

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3
Q

first marker to appear in serum (2-12wks)

A

hbsag

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4
Q

indicator of active infection

A

hbsag

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5
Q

scrng blood donors

A

hbsag

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6
Q

indicates high infectivity and very high transmission (serum)

A

hbeag

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7
Q

present during periods of “active replication” of virus

A

hbeag

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8
Q

not detectablein serum bec of viral env

A

hbcag

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9
Q

detected only in hepatocytes (liver biopsy)

A

hbcag

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10
Q

total ab to hbcag

A

anti-hbc total

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11
Q

used as a marker of acute or chronic hbv infection and a life long marker of past exposure to HBV

A

anti-hbc total

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12
Q

used as a marker of acute hbv infection

A

anti-hbc igm

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13
Q

indicator of present or current infection

A

anti-hbc igm

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14
Q

detect core window period

A

anti-hbc igm

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15
Q

persists for the lifetime of the individual

A

anti-hbc igg

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16
Q

predominant antibody detected in the test for total anti-hbc

A

anti-hbc igg

17
Q

marker for chronic hepatitis

A

anti-hbc igg

18
Q

marker of convalescence and favorable prognosis

A

anti-hbe

19
Q

low infectivity of blood

A

anti-hbe

20
Q

px is recovering from hbv infxn

A

anti-hbe

21
Q

used as a marker of past infxn and also a marker of immunity (immune state)

A

anti-hbs ab

22
Q

response to vaccination

A

anti-hbs ab

23
Q

vacci scr and post-vacci follow up

A

anti-hbs ab

24
Q

hepa C dx test

A

RIBA

inc ALT

25
Q

hepa E dx marker

A

antiHEV igM -acute

HEV RNA -detected in feces (PCR)

26
Q

manifes of IM

A

leukocytosis
>50% lymphocytes
downey cells
atypical reactive lymphocytes

27
Q

heterophile ab

A

forssman ha
serum sickness ha
IM ha

28
Q

sero test for HA

A

paul-bunnel SHEEP
davidsohn differential test
monospot/rapid differential slide test HORSE

29
Q

-
-

A

gp160
gp120 (knobs/spikes)
gp41 (spans inner and outer mem)

30
Q

GAG codes for 3 structural proteins

A

p55 p24 p17

31
Q

POL codes for enz necessary for replication

  • cleaves structual proteins
  • transcribe RNA to DNA
  • inserts viral DNA to host DNA
A

p66 p51

Protease
Reverse transcriptase
Integrase

32
Q

HIV ab detection scr

confirm

A 
scr
ELISA
Microfiltration EIA
Agglu test
----
confirm
WESTERN BLOT
IFA
RIP
33
Q

wetern blot bands

A

p24
gp41
gp120/gp160

SEM2 - I/S (7 decks)

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