Complement part 4 Flashcards

1
Q

dissoc c1r and c1s frm c1q

A

c1 inh

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2
Q

cleaves c3b and c4b

A

factor I

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3
Q

cofactor of I to inactivate c3b; also prevent binding of b to c3b

A

factor h

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4
Q

acts as a cofactor of I to inact c4b

A

c4binding prot

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5
Q

prevents attachment of c5b67 complex to cell membranes

A

s-prot/vitronectin

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6
Q

dissoc of c3 convertase

A

decay accelerating factor

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7
Q

inh membrane attack complex

A

homologous restriction factor

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8
Q

Plasma compo regulation 7

A
c1 inh
factor I
factor h
c4binding prot
s-prot/vitronectin
decay accelerating factor
homologous restriction factor
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9
Q

Deficiencies of complement compo

A
c124
c3
c5678
c9
c1 inh
daf
factor h/factor i
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10
Q

LE like

A

c124

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11
Q

severe recurrent infxn

A

c3

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12
Q

neisser

A

c5678

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13
Q

none

A

c9

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14
Q

hereditary angioedema

A

c1 inh

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15
Q

pnh

A

daf

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16
Q

recurrent bacte infxn

A

factor h or i

17
Q

type 1 2 3 4

A

1anaphylac, 2cyto, 3immune com, 4cell-mediated
1igE, 2G, 3MG, 4Sensi T cell
1baso mast, 2rbc wbc plt, 3host tissue cell, 4macro/T