Immunology Flashcards
1
Q
what is a granuloma?
A
an organised collection of activated macrophages and lymphocytes
2
Q
name some differentials of a lung granuloma
A
sarcoidosis
mycobacterial disease
3
Q
name two common primary antibody deficiencies
A
common variable immune deficiency (CVID)
selective IgA deficiency
4
Q
what immune proteins are low in CVID?
A
IgG
IgA
IgM
5
Q
how does CVID present?
A
recurrent bacterial infections
often associated with autoimmune diseases
6
Q
how does selective IgA deficiency present?
A
2/3 of patients are asymptomatic
recurrent RTIs
7
Q
what does complement deficiency predispose to?
A
bacterial infections - especially meningitis
