Biochemistry Flashcards
what effect does low free T4 have on TSH?
stimulates TSH release
what effect does high free T4 have on TSH?
suppresses TSH
what happens to TSH in hypopituitarism?
TSH cannot be increased despite low free T4, as the negative feedback loop is broken
what blood results can indicate that someone on levothyroxine is over-replaced?
high free T4
low TSH
what side effect is seen following radioactive iodine treatment for hyperthyroidism and when is this usually picked up?
hypothyroidism
usually picked up at 3 months
what condition are tendon xanthomata seen in?
familial hypercholesterolaemia
pathognomic
where are chylomicrons seen in separated serum?
layer on the surface as they rise to the top
what does the efficacy of antidopaminergic anti psychotic drugs correlate with?
the degree of prolactin elevation they cause
what is the most potent statin?
rosuvastatin
