Immunoglobulins/Coombs

Question 1

Ig in Erythroblastosis fetalis

Answer 1

IgM–> can’t cross placenta

IgG –> crosses placenta

Question 2

AIHA:

Warm–>Ig

Answer 2

IgG mediated

Question 3

AIHA:

Cold–> Ig

Answer 3

IgM mediated

Question 4

Direct or indirect Coombs’ test
•
IgG only:

Answer 4

hapten drug absorption type or autoantibody type.

Question 5

Direct or indirect Coombs’ test:

Complement only

Answer 5

ternary complex type (immune-complex type).

Question 6

Acute hemolytic transfusion rxn

Answer 6

Preformed IgM

Question 7

Acute hemolytic transfusion rxn Coomb’s

Answer 7

positive for complement

Question 8

Delayed Transfusion rxn

Answer 8

IgG

Question 9

Delayed Transfusion rxn Coomb’s

Answer 9

positive for IgG

Question 10

CVID:

Igs

Answer 10

They are all decreased;
Significantly reduced total serum IgG
Low IgA and/or IgM

Question 11

Wiskott Aldrich

Answer 11

Inc. IgA and IgE

Dec. IgG and IgM

Question 12

Inc. IgA and IgE

Dec. IgG and IgM

Answer 12

Wiskott Aldrich

Question 13

absence or marked reduction of IgA

Answer 13

ataxia telan

Question 14

Heterophile antibody for EBV

Answer 14

IgM

Question 15

M protein:

Multiple Myloma

Answer 15

IgG or IgA

Question 16

M protein:

Lymphoplasmocytic lymphoma

Answer 16

IgM

Question 17

Heavy chain disease

Answer 17

IgA