CDs Flashcards

1
Q

Pre-cursor B-cells

A

CD10
CD19
CD20

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2
Q

hematopoietic stem cell CD

A

CD34

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3
Q

Hodgkin’s lymphpma CD

A

CD15
CD30
PAX 5

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4
Q

T-cell markers

A

CD2-CD8

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5
Q

Hairy Cell Leukemia CD markers

A

CD45
CD103
CD11c

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6
Q

what CD not found in Hairy cell?

A

NOT CD21

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7
Q

B-cell marker in CLL/SLL

A

CD23

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8
Q

IL-2 receptor

A

CD25

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9
Q

Decay Accelerating Factor

A

CD55

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10
Q

CD59

A

membrane inhibitor of lysis

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11
Q

which B-cell lymphomas have T-cell marker? which T-cell marker

A

CLL/SLL
Mantle Cell
coexpress CD5

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12
Q

lymphocyte predominant CD

A

CD20+

CD15- and CD30-

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13
Q

Adult T-cell lymphoma CD marker

A

CD25 (IL-2 receptor)

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14
Q

Mycosis fungoides CD marker

A

CD4+ T-cell;

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15
Q

CD19, 20, 23 and 5

A

CLL/SLL

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16
Q

Ig light chain and CD19, 20, 22, 45, 103 and annexin but NOT CD21

A

Hairy Cell Leukemia

17
Q

CD10, CD19, CD34;

terminal deoxynucleotidyl transferase [TdT]).

A

Blast Phase (CML)

18
Q

Anti-CD3 monoclonal Ab

A

Depletes T-cells

19
Q

Anti-IL-2 receptor Ab (CD25)

A

blocks T-cell proliferation

20
Q

CTLA4-Ig

A

inhibits T-cell activation

21
Q

Binds to the CD20 antigen on the surface of pre-B cells and mature B cells

A

Rituximab

22
Q

beta2-integrin CD

A

CD18

LADI

23
Q

Reduced numbers of CD3+ T-cells

A

Diagnosis–>DiGeorge Syndrome

24
Q

Drug that is anti-CD3

A

Muromonab

25
Q

Mouse monoclonal Ab against human CD3 (cell surface molecule for T-cell receptor activation)

A

Muromonab

26
Q

Abs against CD25—the high affinity IL-2 receptor

A

Daclizumab and Basiliximab: