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Step 1 Immunology-First Aid 2017 > Immunoglobulin Isotypes > Flashcards

Immunoglobulin Isotypes Flashcards

1
Q

Main antibody in secondary (delayed) response to antibody

A

IgG

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2
Q

Most abundant immunoglobulin in serum, fixes complement and crosses placenta

A

IgG

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3
Q

Which immunoglobulin provides infants with passive immunity

A

IgG

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4
Q

Which immunoglobulin opsonizes bacteria, neutralizes bacterial toxins and viruses

A

IgG

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5
Q

Name the different isotypes of immunoglobulins

A

IgG, IgA, IgM, IgD, IgE

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6
Q

Immunoglobulin that prevents attachment of bacteria and viruses to mucous membranes

A

IgA

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7
Q

Immunoglobulin that does not fix complement

A

IgA

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8
Q

Immunoglobulin found as a monomer in circulation and a dimer with J-chain when secreted

A

IgA

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9
Q

Immunoglobulin that crosses epithelial cells via transcytosis

A

IgA

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10
Q

Immunoglobulin produced in Peyer’s pathches of GI tract and protects against gut infections

A

IgA

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11
Q

Which immunoglobulin will protect against Giardia?

A

IgA

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12
Q

Most produced immunoglobulin with lowest concentrations

A

IgA

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13
Q

Immunoglobulin released in secretions and breast milk

A

IgA

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14
Q

Immunoglobulin produced in the primary (immediate) response to an antigen

A

IgM

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15
Q

Immunoglobulin that fixes complement but does not cross the placenta

A

IgM

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16
Q

Immunoglobulin that functions as antigen receptor on B-cells

A

IgM

17
Q

Immunoglobulin exists as monomer on B-cell and pentamer with J-chain when secreted

A

IgM

18
Q

Which IgM form avidly binds to antigen while humoral response evolves

A

Pentamer

19
Q

What is the function of IgD

A

Unclear function

20
Q

Location of IgD

A

Surface of many B cells and in serum

21
Q

Immunoglobulin that binds mast cells and basophils

A

IgE

22
Q

Immunoglobulin involved in immediate (type I) hypersensitivity reaction

A

IgE

23
Q

Immunoglobulin that cross-links when exposed to allergen causing release of histamine

A

IgE

24
Q

Immunoglobulin that protects against helminthic infections

A

IgE

25
Q

Immunoglobulin with lowest concentration in serum

A

IgE

Step 1 Immunology-First Aid 2017 (30 decks)

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