IMMUNO SERO Flashcards
is the study of a host’s reactions when foreign substances are introduced into the body
IMMUNOLOGY
function of the immune system is to recognize self from nonself and to defend the body against nonselfsystems
responsible for the recognition and disposal of foreign (nonself ) material
IMMUNOLOGY
One of the deadliest diseases known to humans
SMALLPOX
a form of variolation used (in China)
insufflation
study of blood serum (the clear fluid that separates when blood clots)
SEROLOGY
earliest practice of variolation
Lady Mary
Wortley Montagu
generally considered to be the Father of
Immunology for his use of attenuated vaccine
Louis Pasteur
a phenomenon known as phagocytosis and a fundamental
part of the immune response
Elie Metchnnikoff
Components of the natural immune system: Cellular
-Mast cells
-Neutrophils
-Macrophages
Components of the natural immune system: Humoral
-Complement
-Lysozyme
-Interferon
Components of the Adaptive Immune System: Cellular
-T lymphocytes
-B lymphocytes
-Plasma cells
Components of the Adaptive Immune System: Humoral
-Antibodies
-Cytokines
are molecules associated with groups of pathogens that are recognized by cells of the innate immune system.
PAMPs (pathogen-associated molecular patterns )
These inflammatory components liberated from damaged cells include nucleic acids, intracellular proteins, extracellular
matrix components, oxidized lipids, crystals such as uric acids, silica, β-amyloid, and cholesterol
DAMPS (damage associated molecular patterns)
The receptors of the innate immune system that recognize these PAMPs are called
pattern recognition receptors (PRRs)
Three groups of PRRs exist
- Secreted PRRs
- Phagocytosis receptors
- Toll-like receptors (TLRs)
type of adaptive immunity
- antibodies from mother to child
*immunoglobulins for rabies infection - attenuated vaccines
- Toxoids
- Convalescence plasma treatment
a substance that stimulates antibody
formation
antigen