Immunity Disorders Flashcards

1
Q

Allergy

A

The inappropriate response of the immune system to certain antigens is called allergy

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2
Q

Other name of allergy

A

Hypersensitivity

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3
Q

Antobodies production on allergy

A

IG E

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4
Q

Substance causing allergy

A

Allergens

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5
Q

What happens on first contact?

A

IGE produced bind to the FC receptors of mast cells and basophils
This is called sensitisation

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6
Q

What happens on 2nd contact?

A
Allergen cross links between two FC receptors and this causes the degranulation of mast cells and it releases
Histamine
Bradykinin
Serotonin
Prostaglandins
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7
Q

What happens when histamine is released?

A
Dilutes the blood vessels
Oedema- swelling
And redness- erythema 
Contraction is smooth muscle
This attracts the neutrophils and eosinophils
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8
Q

Asthma

A

Allergic reaction on the lower respiratory tract

Sneezing, difficulty in breathing( due to constriction in smooth muscle), running nose

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9
Q

How to control asthma

A

Aerosol inhalants

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10
Q

For determining cause of allergy what is done ?

A

Very small dose of possible alergen is given to patients and then quickly Anti histamine, steroids, adrenalin is given to reduce the symptoms

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11
Q

How to desensitised allergy

A

Giving injections of the antigen which leads to the formation of blocking antibodies IgG

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12
Q

Anaphylaxis

A

Serious life threatening allergic reaction

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13
Q

Common anaphylactic reaction

A

Food, insect stings,meditation,and latex

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