Cancer Flashcards
Branch of science which deals with tumours
Oncology
Non cancerous cells
Benign tumour Do not show metastatis Removed by surgery Fibrous outer capsule Ex: uterine fibroids
Per malignant tumour
Sarcinoma in situ
Cells transform into cancerous cells in due course of time
Malignant tumour
Harmful
Metastatis
Mass of neoplasticism cells
Ex: lukemia
Characters of cancer cells
Uncontrolled growth- no limit of growth unlimited growth
Metastasis normal cells join with each other and have controlled growth due to cadherins* but cancer cells keep on growing in size and move from one place to other to cause cancer in Other parts
Over abundance of telomerase enzyme- cancer cells never age . Keep on growing
Surface antigens- if antigen detected, then destroyed by NK and Tc cells
Angiogenesis- ability of cancer cells to attract the blood vessels leading to O2 deficiency in normal cells
Failure of apoptosis- resist the programmed cell death. Helps in the development of tumour
Epithelial cells cancer
Carcinoma
Eg: Brest cancer( adenocarcinoma), brain tumours
85% of the cancers diagnosed are carcinomas
Connective tissue cancer
Sarcoma
From mesoderm
Osteosarcoma of bone, chondrosarcoma of cartilage, angiosarcoma of blood vessels
**Cancer cells of muscles are also sarcoma
Cancer to RBC
Leukaemia
Tumour of secondary lymphoid organs
Lymphoma
Eg: burkit lymphoma
Cancer of pigment cells
Melanoma
Human papilloma virus causes
Cervical cancer
Protein P53
Guardian angel of cell genome
Mutation in genes leads to
Formation of oncogens
Biopsy
A piece os suspected tissue is taken and cut into thin section and examined
**cancer cells have very high value of karyoplasmic index
Radiography
X-ray
MRI- magnetic fields are used
CT- scan- 3D image