Immune System Histology Flashcards
What 5 components make up the innate immune response
Epithelial surfaces
Macrophages
Dendritic cells
Natural killer cells
Complement system
Innate immune epithelial surface
Prevent entry of pathogens
Innate immune macrophages
Receptors on macrophages recognize foreign molecules . The receptors on macrophages ingest and kill the pathogens
Cytokines
Contribute to inflammatory response
Dilation of blood vessels
Increase temperature
Blood clotting
Can activate proliferation of T cells
What other cells are able to trap pathogens and present antigens
Dendritic cells
Natural killer cells
Recognize and selectively kill virus infected cells and cancer cells
Adaptive immune response components
T lymphocytes
B lymphocytes
Plasma cells = activated B lymphocytes
Antigen presenting cells
Two types of adaptive response
Cell mediated response
Antibody response
Cell mediated response
T cells kill pathogen infected cells
Help activate B cells
Antibody response
Activates B cells
Secrete antibodies that neutralize the pathogen
What are antibodies produced by
Activated B cells in response to foreign molecule
Bone marrow contains
Stem cells for T and B cells
Allows for some B lymphocyte differentiation
Thymus
Maturation of T cells
Thymus epithelioreticular cells
Form blood thymus barrier
Nurse cells to the maturing T cells
M cells
Form a pocket containing macrophages, dendritic cell, T cells and B cells
Capture antigens and deliver them directly to macrophages