immune system Flashcards

1
Q

antigen

A

foreign molecule
- induces rsp to immune system

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2
Q

antigen are recognized by ___ part of molecule at _______

A

small
antigenic determinant

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3
Q

Humoral immunity is

A

production of antibody in rsp to antigen

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4
Q

Phagocytosis occurs when

A

body detects antibody
- prmly by neutrophils & macrophages

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5
Q

lymphatic vessels

A

carry lymph
drains fluid from tissues back to lymph nodes & eventually bloodstream

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6
Q

stocking up condition occurs when

A

lack of activity -> fluid build up in legs b/c difficulty fighting gravity

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7
Q

immunity sites include the

A

spleen and bone marrow

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8
Q

spleen found in

A

w/in abdomen
large, reddish brown organ

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9
Q

___ alters blood just as lymph nodes modify lymph

A

spleen

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10
Q

spleen contains ____ of ____ immune cells & antigen-rspding cells

A

large #
antigen-scanning

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11
Q

spleen extracts ____ from circulation

A

aged RBCs

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12
Q

bone marrow is a _____ of immune system

A

essential component
- produces WBCs

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13
Q

list the roles of cytokines

A
  • kill/slow down replication of viruses
  • attract other immune cells to site
  • facilitates phagocytosation of antigens
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14
Q

_____ of body = impnt part of compelte physical examination

A

temp control

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15
Q

high body temp promotes mvt of ___,___, & ___

A

lymphocytes
phagocytes
antibodies

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16
Q

higher temp(AKA fever) can ___/___ replication of infectious organism

A

hinder/kill

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17
Q

Inflammation can result from

A

physical injury
rxn to pathogen’s invasion

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18
Q

inflammation can cause ___ of local blood vessels & _______ of capillaries

A

dilation
increase permeability

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19
Q

why does inflammation cause swelling

A

higher permeability -> more fluid to penetrate tissues -> edema/swelling

extra fluid -> higher pressure -> compressing ends of tissues

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20
Q

symptoms of inflammation

A

discomfort
- warmth, redness, edema, pain

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21
Q

Clonal expansion is

A

increase large # of lymphocytes designated to rspd to specific antigen

-> increase a lot of lymphocytes to rspd to an antigen

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22
Q

one type of lymphocyte is

A

Lymphocyte B cell
- from bone marrow
- many dvp into plasma cells during clonal expansion

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23
Q

plasma cells

A

secretes particular type of protein - known as antigen/humoral immunity

24
Q

to stmte immune rsp ->

A

pathogen must overcome body’s general protective defense

  • proves that it can survive past auto -> needs more assistance to kill off
25
pathogen entry points include
superficial mucous membranes - nose, mouth, eyes
26
T/F physical elimination of invading pathogens is possible
TRUE - ex. urine passes through urethra
27
innate immunity
non-specific rsp (phagotic cells eat bacteria) body itself is able to take care of the pathogens
28
in tissues - phagocytic cells are
present to swallow any bacteria that passes physical defenses
29
T/F neutrophils are NOT involved in phagocytosis and do not provide initial rsp
FALSE - neutrophils provide initial rsp (front line) and ARE involved in phagocytosis (body detecting antigen)
30
what do neutrophils NOT act as
antigen-presenting cells - dont induce another immune rsp
31
tissue macrophages come from
monocytes leaving bloodstream
32
tissue macrophages ____ to ____ activity & ___ dmged areas
react neutrophil invade
33
T/F cells like tissue macrophages are HIGHLY EFFECTIVE in phagocytosis
TRUE
34
how long does it take for body to produce substantial amt of antibody after being exposed to antigen
3-14 days
35
how long do plasma cells live for
4-5 days w/enormous demand
36
difference b/w clonal cells and plasma cells
clonal cells can grow into MEMORY cells - plasma cant
37
advantages of memory cells
- live long - fast rsp when same antigen next time - less antigen needed - memory - literally, rmb antigen and how to kill
38
secondary reaction
- prevents anml from dvping a 2nd time - common diseases (flu/cold) = many strains = diff e/t = don't stmt 2nd rsp
39
what type of lymphocyte cells does body have large supply of
T cell and B cell
40
what lymphocyte cell comes from bone marrow and matures in thymus gland
T cell
41
T/F not every T cell is responsive to a specific antigen determinant
FALSE EVERY T cell = rspve
42
how does cell-mediated immunity typically work
works in conjunction w/humoral immunity
43
what are the 2 types of T cells
T-helper cell cytotoxic cell
44
how does t-helper cells stmte immune rsp and how do they detect cancer cells
release cytokines cancer cells = diff surface antigen
45
Can B-cells become memory B cells?
YES - but NOT LONG-LIVED - not exactly like memory cells from clonal cells
46
disease protection can come from
natural infection or vaccination -> active immunity
47
how does vaccine provide protection
prepares anml to rspd fast to disease
48
T/F vaccine/immunication are based on memory cell dvpmt
TRUE
49
name the 2 types of vaccines and how they work
modified live vaccine - from pathogen's modified strains - strain = weakened => replicate but not harmful killed vaccine - dead pathogen - can't divide, but still has antigen to induce immune rsp
50
what dvps when transferring antibodies from 1 anml to another
passive immunity
51
what is colostrum
- 1st milk from mom during pregnancy - very rich in antibodies (whatever mom has, passes to kid) - how kid defends itself as a new born
52
antibodies are digested & _____ through normal ____
inactivated digestion
53
antibodies are
protein molecules
54
if antibody is absorbed through blood stream, newborn will have
instant immunity
55
T/F ability to absorb antibodies is rapidly INCREASING
FALSE - rapidly descreasing