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Pathophysiology > Immune System > Flashcards

Immune System Flashcards

1
Q

What cells are in innate immunity?

A

Neutrophil, Natural killer cell, dendritic cell, macrophage

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2
Q

What are the types of adaptive immunity?

A

Humoral and cell mediated

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3
Q

What cells are in adaptive humoral immunity?

A

B lymphocytes, memory cells, plasma cells

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4
Q

What cells are in adaptive cell mediated immunity?

A

CD8 cells, CD4 cells, suppressor T cells

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5
Q

What cells are in Lymph immunity?

A

Naïve T lymphocytes, Naïve B lymphocytes

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6
Q

What are natural killer cells?

A

antigen destruction

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7
Q

What do dendritic cells do?

A

present antigens

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8
Q

What do neutrophils do?

A

phagocytosis

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9
Q

What do macrophages do?

A

phagocytosis

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10
Q

What do monocytes mature into?

A

Macrophages

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11
Q

What is an IgA antibody?

A
  • From mother, passive immunity
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12
Q

What is an IgG antibody?

A
  • Crosses placenta, provides passive immunity
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13
Q

What is an IgM antibody?

A
  • Produced in response to antigen
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14
Q

What is IgD antibody?

A
  • Antigen binding and stimulation differentiation of B lymphocytes into plasma cells
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15
Q

what is IgE antibody?

A
  • Allergens
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16
Q

What is a Type 1 hypersensitivity reaction?
- Mediated by?
- Response?
- Causes?

A
  • Mediated by IgE
  • Immediate response
  • Allergic reaction
  • Anaphylaxis
17
Q

What is a Type 2 hypersensitivity reaction?

A
  • Mediated by IgG or IgM
  • Tissue/organ specific
18
Q

What is a Type 3 hypersensitivity reaction?

A
  • IgG or IgM
  • Immune complex
  • Systemic
19
Q

What is a Type 4 hypersensitivity reaction?

A
  • Mediated by T Cell
  • 24-72hr response delay
  • Posion ivy
20
Q

Extrinsic pathway time to complete, example?

A
  • Shorter
  • Cut finger
21
Q

Intrinsic pathway speed and example?

A
  • Slower
  • Damaged inside
22
Q

What does fibrinogen and thrombin make?

A

Fibrin

23
Q

What do Cytotoxic T Cells (CD8) do?

A

Destroy antigen

24
Q

What do helper T Cells (CD4) do?

A

Activate antigen specific cell (CD8)

25
Q

What do suppressor T cells do?

A

Inhibit humoral and cell mediated response

26
Q

What do human leukocyte antigens do?

A
  • Recognize antigens from self vs nonself
27
Q

What is a dendritic cell?

A

Antigen presenting cell

28
Q

What do effector cells do?

A

Secrete large amounts of antibodies

Pathophysiology (6 decks)

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